Results 181 to 190 of about 93,399 (264)

A case of bilateral oophorectomy in a 40-day-old female due to a misdiagnosis of complete androgen insensitivity syndrome. [PDF]

Ann Med Surg (Lond)
Chreitah A, Abo Kaf B, Aljanati O, Alkilany Z, Issa M, Jraikoos I.   +5 more
europepmc   +1 more source

Population Pharmacokinetic Analysis of Datopotamab Deruxtecan (Dato‐DXd), a TROP2‐Directed Antibody‐Drug Conjugate, in Patients With Advanced Solid Tumors

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Datopotamab deruxtecan (Dato‐DXd) is a trophoblast cell surface antigen 2 (TROP2)‐directed antibody‐drug conjugate (ADC) developed for the treatment of advanced or metastatic solid tumors. Dato‐DXd demonstrated promising antitumor activity and a manageable safety profile in the first‐in‐human Phase 1 study TROPION‐PanTumor01.
Ying Hong, Sophie Peigné, Υuzhuo Pan, Sofia Friberg Hietala, Anna McLaughlin, Naoyuki Tajima, Deise Uema, Hong Zebger‐Gong, Zoey Tang, Diansong Zhou, Malaz Abutarif, Τushar Garimella   +11 more
wiley   +1 more source

The impact of hormonal fluctuations and the efficacy of targeted hormonal interventions in improving macular hole outcomes. [PDF]

Front Med (Lausanne)
Ni L, Ma L, Fan M, Zhang L.
europepmc   +1 more source

Upconverting Nanoparticle‐Loaded Microneedles for Near‐Infrared Responsive Delivery of Gonadotropins to Increase Success of In Vitro Fertilization

Small, EarlyView.
This paper describes the development of an upconverting particle‐integrated microneedle patch that can release the hormone leuprolide when the patch is exposed to near‐infrared light. This system represents proof‐of‐concept of a painless and automated method of delivering drugs at specific times when repeated time‐sensitive injections are required ...
Vivienne Tam, Rusvir Trana, Alfonso Nieto‐Arguello, Ore‐Oluwa Olasubulumi, Samuel Babity, Artiom Skripka, Fiorenzo Vetrone, Davide Brambilla, Marta Cerruti   +8 more
wiley   +1 more source

Impact of sex hormones on postoperative outcomes in plastic surgery: a narrative review. [PDF]

Front Surg
Lv X, Xiang C, Zheng Y, Lv X, Zhou W, Zhu J.   +5 more
europepmc   +1 more source

Spongiosolysis [PDF]

, 1987
Gilbert, P., Stief, Christian Georg
core   +1 more source

Putting the Femme in Feminist: Trans Feminism and the ‘Male Lesbian’ in the American Second Wave

Gender &History, EarlyView.
ABSTRACT A slur, a joke or a post‐structuralist case of mistaken identity. To the extent that the male lesbian has been discussed, she has figured dismissively. Yet throughout the period historicised as American feminism's second wave, potentially thousands of trans femmes organised under this identity. Despite being entirely overlooked in scholarship,
Aino Pihlak, Emily Cousens
wiley   +1 more source

Androgen receptor mutations in familial androgen insensitivity syndrome: A metabolic reprogramming pathway to type 2 diabetes susceptibility. [PDF]

World J Diabetes
Luo C, Zhang WW, Hua LY, Zeng MQ, Xu H, Duan CZ, Xu SY, Zhan S, Pan XF, Sun D, Ye LY, He DJ.   +11 more
europepmc   +1 more source

Spatiotemporal Crosstalk Between Oocyte and the Microenvironment Governs Preovulatory Follicle Aging

Aging Cell, EarlyView.
Preovulatory follicle aging is characterized by two distinct phases—early oocyte protective and late degenerative phases. The degenerative phase involves a positive feedback loop between oocyte mitochondrial dysfunction mediated by a mitochondrial‐localized microprotein PIGBOS, and granulosa cell functional decline through a circular RNA circdlg1 ...
Xin Yi Koh, Kah Junn Tan, Zeng Hao Lim, Shi Chee Ong, Sophie Emma Tan, Jing Xuan Lu, Zhongwei Huang, Jun Wei Pek   +7 more
wiley   +1 more source

Breast Cancer in Female to Male Transsexuals Before and After Mastectomy Surgery; A Case Report and Literature Review. [PDF]

Clin Case Rep
Najafizadeh-Sari S, Javanbakht M, Rezaee M.   +2 more
europepmc   +1 more source