Pharmacologic MRI Brain Imaging Studies of Serotonin 5‐HT1 Receptor Agonists in Awake Mice
ABSTRACT Serotonin (5‐hydroxytryptamine, 5‐HT) type‐1 G protein‐coupled receptors are expressed throughout the central nervous system. 5‐HT1AR activation is the putative mechanism of approved drugs for generalized anxiety disorder and major depressive disorder and is being studied in the treatment of autism and neurological disorders.
Brittany M. Brems +5 more
wiley +1 more source
Evolutionary Footprint: A Systemic Indicator in Evolution, Ecology and Conservation
ABSTRACT The growing awareness of evolutionary responses to human‐induced environmental changes highlights the need to better understand and integrate evolutionary perspectives into life sciences and, more broadly, into biodiversity conservation. Evolutionary changes are complex and multi‐causal, operating across numerous timescales.
Thibault Genissel +3 more
wiley +1 more source
Abstract This study aims to provide a detailed characterization of luteinizing hormone (LH) pulsatility in male and female Sprague–Dawley and Wistar rats, utilizing a minimally invasive tail‐tip blood sampling approach across various reproductive states.
Nabil Nasri +2 more
wiley +1 more source
Persistent Horner Syndrome Following Bilateral Endoscopic Thoracic Sympathotomy: A Case Report. [PDF]
Lee HJ, Kang JJ, Oh SY.
europepmc +1 more source
ABSTRACT Identifying close relatives in wild animal populations is fundamental across many research fields. Genetic estimates of relatedness have expanded rapidly in recent decades, drawing on a range of genetic data types. Here, we review their use and outline opportunities for future studies by combining two complementary approaches.
Annika Freudiger +7 more
wiley +1 more source
Recent Polygenic Adaptation in Heavily Fished Malawi Cichlids
ABSTRACT Intense fishing pressure can drive rapid evolution in wild populations, yet the underlying genomic mechanisms often remain elusive. Here, we investigate the genomic consequences of five decades of intense harvesting on the cichlid fish Copadichromis mloto in Lake Malombe, Malawi.
Alexander Hooft van Huysduynen +5 more
wiley +1 more source
Harlequin sign associated with Horner syndrome secondary to an 11 cm left upper lung lobe adenocarcinoma. [PDF]
Li Y, Moon DJ, Linden KG.
europepmc +1 more source
Awake Percutaneous Cervical Cordotomy in Patients With Cancer: A Technical Report
ABSTRACT Background Percutaneous cervical cordotomy (PCC) is a minimally invasive radiofrequency procedure for intractable unilateral cancer pain. Commonly performed under conscious sedation, awake PCC enables real‐time patient feedback, potentially improving targeting precision and expanding eligibility for patients in whom sedation poses risks ...
Adinda P. Pradhana +6 more
wiley +1 more source
The evidence for old age motor neuron death: A scoping review
We systematically evaluated the extant literature on age‐related motor neuron (MN) death in aging, focusing on studies directly assessing MNs. We show that in the spinal cord and brainstem, there is robust evidence for MN loss, particularly in the human spinal cord. In rats, MN loss was readily observed across a variety of labelling methods and regions,
Sang Won Cheung, Matthew J. Fogarty
wiley +1 more source
Using AI Text-to-Image Generation to Create Novel Illustrations for Medical Education: Current Limitations as Illustrated by Hypothyroidism and Horner Syndrome. [PDF]
Kumar A, Burr P, Young TM.
europepmc +1 more source

