Results 171 to 180 of about 5,752 (241)

Pharmacologic MRI Brain Imaging Studies of Serotonin 5‐HT1 Receptor Agonists in Awake Mice

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Serotonin (5‐hydroxytryptamine, 5‐HT) type‐1 G protein‐coupled receptors are expressed throughout the central nervous system. 5‐HT1AR activation is the putative mechanism of approved drugs for generalized anxiety disorder and major depressive disorder and is being studied in the treatment of autism and neurological disorders.
Brittany M. Brems   +5 more
wiley   +1 more source

Evolutionary Footprint: A Systemic Indicator in Evolution, Ecology and Conservation

open access: yesEvolutionary Applications, Volume 19, Issue 6, June 2026.
ABSTRACT The growing awareness of evolutionary responses to human‐induced environmental changes highlights the need to better understand and integrate evolutionary perspectives into life sciences and, more broadly, into biodiversity conservation. Evolutionary changes are complex and multi‐causal, operating across numerous timescales.
Thibault Genissel   +3 more
wiley   +1 more source

Pulsatile LH release in male and female Sprague Dawley and Wistar rats in different reproductive states

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 6, June 2026.
Abstract This study aims to provide a detailed characterization of luteinizing hormone (LH) pulsatility in male and female Sprague–Dawley and Wistar rats, utilizing a minimally invasive tail‐tip blood sampling approach across various reproductive states.
Nabil Nasri   +2 more
wiley   +1 more source

Genetic Estimates of Relatedness: Established Practices and New Opportunities Through Low Coverage Whole‐Genome Sequencing

open access: yesMolecular Ecology, Volume 35, Issue 11, June 2026.
ABSTRACT Identifying close relatives in wild animal populations is fundamental across many research fields. Genetic estimates of relatedness have expanded rapidly in recent decades, drawing on a range of genetic data types. Here, we review their use and outline opportunities for future studies by combining two complementary approaches.
Annika Freudiger   +7 more
wiley   +1 more source

Recent Polygenic Adaptation in Heavily Fished Malawi Cichlids

open access: yesMolecular Ecology, Volume 35, Issue 12, June 2026.
ABSTRACT Intense fishing pressure can drive rapid evolution in wild populations, yet the underlying genomic mechanisms often remain elusive. Here, we investigate the genomic consequences of five decades of intense harvesting on the cichlid fish Copadichromis mloto in Lake Malombe, Malawi.
Alexander Hooft van Huysduynen   +5 more
wiley   +1 more source

Awake Percutaneous Cervical Cordotomy in Patients With Cancer: A Technical Report

open access: yesPain Practice, Volume 26, Issue 5, June 2026.
ABSTRACT Background Percutaneous cervical cordotomy (PCC) is a minimally invasive radiofrequency procedure for intractable unilateral cancer pain. Commonly performed under conscious sedation, awake PCC enables real‐time patient feedback, potentially improving targeting precision and expanding eligibility for patients in whom sedation poses risks ...
Adinda P. Pradhana   +6 more
wiley   +1 more source

The evidence for old age motor neuron death: A scoping review

open access: yesPhysiological Reports, Volume 14, Issue 11, June 2026.
We systematically evaluated the extant literature on age‐related motor neuron (MN) death in aging, focusing on studies directly assessing MNs. We show that in the spinal cord and brainstem, there is robust evidence for MN loss, particularly in the human spinal cord. In rats, MN loss was readily observed across a variety of labelling methods and regions,
Sang Won Cheung, Matthew J. Fogarty
wiley   +1 more source

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