Results 141 to 150 of about 1,243,200 (309)
Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Advanced Science, EarlyView.Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source
Brazilian Sport Horse: Pedigree Analysis of the Brasileiro de Hipismo Breed
, 2014 Bethânia Rocha Medeiros +3 more
openalex +1 more source
OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain
Advanced Science, EarlyView.OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang +10 more
wiley +1 more source
Information-Analitical Support of Cost Management in Horse Breeding
, 2014 Гузалия Клычова
openalex +2 more sources
Show Quality Quarter Horse Auctions: Price Determinants and Buy-Back Practices [PDF]
This study estimates the price determinants of show quality quarter horses sold at auction. Several characteristics including genetic and physical traits, quality of pedigree, and performance record of the horse, as well as the horse's offspring, were ...
Dhuyvetter, Kevin C. +4 more
core +1 more source
Advanced Science, EarlyView.By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang +27 more
wiley +1 more source
THE HORSE SECTOR: DOES IT MATTER FOR AGRICULTURE? [PDF]
EU policies focus ever more on rural development initiatives. The horse sector provides some opportunities. An I/O model is used to examine the aggregate effects of the horse sector on Swedish agriculture. The maximal potential of the sector accounts for
Andersson, Hans, Johansson, Dag
core +1 more source
Advanced Science, EarlyView.A bioorthogonal rhodamine/PEG crosslinking strategy is introduced to engineer dense collagen hydrogels with high mechanical resilience and cytocompatibility. Integration with wet‐spinning enables the fabrication of uniaxially aligned, cell‐laden collagen filaments that activate mechanotransductive signaling and support functional muscle regeneration in
JuYeon Kim +4 more
wiley +1 more source
Equine degenerative myeloencephalopathy: prevalence, impact, and management. [PDF]
, 2018 Equine neuroaxonal dystrophy/equine degenerative myeloencephalopathy is an inherited neurodegenerative disorder affecting many horse breeds. Clinical signs include a symmetric ataxia and an abnormal stance at rest, similar to cervical vertebral ...
Burns, Erin N, Finno, Carrie J
core
Advanced Science, EarlyView.This study identifies a unique physical signature of colorectal cancer in younger adults: their tissues are mechanically stiffer than those in older patients with the same cancer. Furthermore, stromal remodeling in early‐onset colorectal cancer promotes epithelial mechanotransduction and proliferation, showing how mechanical alterations in the tissue ...
Nicole C. Huning +18 more
wiley +1 more source