Results 41 to 50 of about 9,585,376 (354)

Differences in microbiome and virome between cattle and horses in the same farm [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2020
Objective The ecosystem of an animal farm is composed of various elements, such as animals, farmers, plants, feed, soil, and microorganisms. A domesticated animal’s health is largely connected with the reservoir of bacteria and viruses in animal farms ...
Jongbin Park, Eun Bae Kim
doaj   +1 more source

Vaccination Status of Horses in Poland Based on an Internet Survey of the Horse Owners

open access: yesAnimals
Preventing the spread of infectious diseases in horses requires breaking the chain of infection through appropriate prophylaxis. In Poland, where the horse population reached 273,006 in 2023, vaccinations are voluntary and primarily the responsibility of
Marta Rykala   +2 more
doaj   +1 more source

The occurence of some pests and diseases on horse chestnut, plane tree and Indian bean tree in urban areas of Slovenia

open access: yesActa Agriculturae Slovenica, 2004
The occurrence of some pests and diseases was monitored on horse chestnut (Aesculus hippocastanum), red horse chestnut (Aesculus x carnea), plane tree (Platanus hybrida) and Indian bean tree (Catalpa bignonioides) in the period 1995-2003.
Lea MILEVOJ
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Molecular surveillance of tick‐borne diseases affecting horses in Poland—Own observations

open access: yesVeterinary Medicine and Science, 2021
The purpose of the study was to carry out the molecular surveillance of piroplasmosis, granulocytic anaplasmosis and lyme borreliosis in horses which originated from Poland and exhibited symptoms raising the suspicion of the aforementioned disease units.
Oliwier Teodorowski   +5 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Whole-Genome sequencing and genetic variant analysis of a quarter Horse mare

open access: yesBMC Genomics, 2012
Background The catalog of genetic variants in the horse genome originates from a few select animals, the majority originating from the Thoroughbred mare used for the equine genome sequencing project.
Doan Ryan   +5 more
doaj   +1 more source

Trojan Horse Antibiotics—A Novel Way to Circumvent Gram-Negative Bacterial Resistance?

open access: yesInfectious Diseases, 2016
Antibiotic resistance has been emerged as a major global health problem. In particular, gram-negative species pose a significant clinical challenge as bacteria develop or acquire more resistance mechanisms.
G. Tillotson
semanticscholar   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

D159 and S167 are protective residues in the prion protein from dog and horse, two prion-resistant animals

open access: yesNeurobiology of Disease, 2018
Prion diseases are fatal neurodegenerative diseases caused by misfolding of the prion protein (PrP). These conditions affect humans and animals, including endemic forms in sheep and deer.
Jonatan Sanchez-Garcia   +1 more
doaj   +1 more source

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