Results 171 to 180 of about 46,045 (257)

Neurocognitive Aging Following Acute Illness: Pathobiology and a Framework for Developing Neurotherapeutic Agents

open access: yesBrain and Behavior, Volume 16, Issue 6, June 2026.
In this review, we discuss the scientific basis for how neurocognitive aging occurs after critical illness, including sepsis, trauma, and burns, and the clinical need to develop therapies to reduce inflammation, protect the blood–brain barrier, remove senescent cells, and enhance neuroplasticity.
Errin Lawrence   +14 more
wiley   +1 more source

Metastatic Ewing Sarcoma, Patterns of Care and Outcomes of Patients in a Real‐Life National Setting Over a Decade

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Metastatic Ewing sarcoma (MES) has a poor prognosis. This multicenter observational study provides real‐world data on treatment patterns of patients with MES in France. Treatment characteristics, outcomes such as time to next treatment (TTNT) and overall survival (OS), and prognostic factors of patients aged ≥ 12 years treated for a MES in 11 ...
Coline Ducrot   +24 more
wiley   +1 more source

Cancer‐Directed Therapy in the Last Month of Life and Its Association With ICU Utilisation in a Tertiary Care Centre in India

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Use of cancer‐directed therapies (CDT) near the end of life is an established indicator of quality in oncology care. However, evidence from low‐ and middle‐income countries (LMICs), including India, remains limited. Objectives To describe patterns of cancer‐directed therapy use in the last month of life and to evaluate the ...
Kunal Das   +8 more
wiley   +1 more source

Real‐World Evidence of Treatment Patterns, Time to Real‐World Progression, and Overall Survival of Patients With Testicular Germ Cell Tumors Receiving Palliative Chemotherapy in the United States

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Introduction Patients with relapsed/refractory (R/R) testicular germ cell tumor (GCT) progressing after salvage chemotherapy only have palliative therapeutic options. Real‐world data on this population are needed. Methods Adult men with testicular GCT receiving palliative chemotherapy in the United States were identified in the Komodo Research
Darren R. Feldman   +6 more
wiley   +1 more source

When Chronic Pain Clouds Acute Diagnosis: Femoral Shaft Osteonecrosis With Superimposed Pseudomonas Osteomyelitis in a Medically Complex Patient

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT In medically complex patients with chronic pain, new or worsening symptoms should prompt careful reassessment. Avascular necrosis, particularly in the setting of prolonged steroid use, may be overlooked due to diagnostic overshadowing. Timely recognition requires multidisciplinary collaboration and vigilance to distinguish acute pathology from
Ji‐Hoon Lee   +3 more
wiley   +1 more source

Preparation of Medicare‐Enrolled Mental Health Counselors: Descriptions of Training Experiences and Predictors of Attitudes and Competencies

open access: yesCounselor Education and Supervision, Volume 65, Issue 2, Page 129-140, June 2026.
ABSTRACT Counselors are newly eligible to enroll as providers in the Medicare program as of January 1, 2024, yet little is known about their preparedness to work with Medicare beneficiaries and related training experiences. This gap in the literature inhibits our understanding of historical and current counselor education practice, thereby preventing ...
Jordan B. Westcott   +5 more
wiley   +1 more source

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