Results 201 to 210 of about 68,759 (241)

Amyloid β alters vascular CaV1.2 channel spatiotemporal properties

The Journal of Physiology, EarlyView.
Abstract figure legend Amyloid‐β1‐42 (Aβ1‐42) triggers a male‐specific signalling cascade influencing CaV1.2 spatiotemporal properties in cerebral vascular smooth muscle. The signalling pathway involves NADPH oxidase (NOX)‐derived reactive oxygen species (ROS) activation of protein kinase C (PKC). Aβ1‐42 can also activate protein kinase A (PKA).
Jade L. Taylor, Miguel Martin‐Aragon Baudel, Eric Pereira da Silva, Johannes W. Hell, Madeline Nieves‐Cintron, Manuel F. Navedo   +5 more
wiley   +1 more source

Plasma KL-6 reflects pulmonary severity and longitudinal response to enzyme replacement therapy in acid sphingomyelinase deficiency type B. [PDF]

Mol Genet Metab Rep
Cifuentes-Uribe K, Guffon N, Boulière L, Turquier S, Acquaviva-Bourdain C, Froissart R, Pettazzoni M.   +6 more
europepmc   +1 more source

Professionals and the Ethics of Workplace Surveillance

Journal of Social Philosophy, EarlyView.
Steve Clarke, William Tuckwell, Morgan Luck   +2 more
wiley   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

Wellness enhancement for caregivers 2.0: feasibility, acceptability, and preliminary 12‐month outcomes for Chinese American dementia caregivers

Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 4, December 2026.
Abstract INTRODUCTION Chinese American dementia caregivers face cultural, linguistic, and service‐access barriers, yet evidence on culturally tailored digital support and 12‐month caregiver outcomes remains limited. METHODS In a single‐arm pilot, 48 caregivers received the 7‐week Chinese‐language Wellness Enhancement for Caregivers 2.0 (WECARE 2.0 ...
Yi‐Wen Li, Kang Shen, Y. Alicia Hong, Ye (Ashley) Gao, Lily Wang, Huixing Kate Lu, Weijing Shi, Rui Huang   +7 more
wiley   +1 more source

Renal replacement therapy in type 2 severe cardiorenal syndrome: a randomized controlled trial. [PDF]

ESC Heart Fail
Schleef M, Sens F, Magaud L, Haesebaert J, Langlois-Jacques C, Sebbag L, Juillard L, Bonnefoy E, Baudry G, UF-CARE Study Group .   +9 more
europepmc   +1 more source

National Trends and Disparities in Cancer Mortality Among Individuals With Alzheimer's Disease and Related Dementias in the United States, 1999–2020

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT As population aging accelerates, the coexistence of cancer and Alzheimer's disease and related dementias (ADRD) is becoming increasingly common. While each condition independently contributes to mortality, national trends in cancer‐related deaths occurring alongside ADRD—and their demographic and geographic disparities—remain poorly defined ...
Aasim Ali, Javed Iqbal, Aimen Anwaar Pannun, Muhammad Talha, Fiza Nisar, Ufaq Reyaz, Muhammad Saad Ansari, Sameen Sarfaraz, Ahmad Butt, Hammad Azam, Muhammad Shamoon, Labeeba Abdul Ghafoor, Armaghana Abdullah, Muhammad Asad Shabbir, Mukesh Kumar Sharma   +14 more
wiley   +1 more source

The Rising Burden of Atrial Fibrillation and Respiratory Failure Mortality in the United States: A 25‐Year Nationwide Retrospective Analysis of Death Certificate Data

Journal of Arrhythmia, Volume 42, Issue 6, December 2026.
Age‐adjusted mortality rates for deaths recording both atrial fibrillation and respiratory failure among U.S. adults aged ≥ 55 years rose about five‐fold from 1999 to 2024. The rise began before the COVID‐19 pandemic, persisted after excluding deaths listing COVID‐19, and occurred with and without heart failure recorded.
Syed Tawassul Hassan, Naveed Ahmad, Syeda Lyba Onaiz, Anushah Faheem Ilyas, Shiva Kumar, Ali Jan Yaqubi   +5 more
wiley   +1 more source

Optimization of spectral photon-counting CT reconstruction parameters for improved detection of peritoneal metastases compared with energy-integrating detector dual-energy CT: a phantom study. [PDF]

Eur Radiol Exp
Greffier J, Grange R, Dabli D, Houmeau A, Antonuccio MN, Rousset P, Si-Mohamed S.   +6 more
europepmc   +1 more source

Oncology Inpatient Resuscitation Planning and Long‐Term “Rapid Response Call” Outcomes

Asia-Pacific Journal of Clinical Oncology, Volume 22, Issue 6, Page 801-807, December 2026.
Optimal end‐of‐life care involves a patient‐centered approach. The dual audits presented in this study show that a proportion of oncology patients receiving palliative‐intent cancer treatment continue to be managed in hospital without a resuscitation plan and may undergo care escalation to a “rapid response” intervention despite poor prognosis ...
Dhanashree Tikhe, Petition Nhira, Megan Kepreotis, Fiona Day   +3 more
wiley   +1 more source