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Evidence and Equity Gaps in Clinical Care of Chronic Lymphocytic Leukaemia in Portugal: A Real‐World, Multicentre, Cohort Study

eJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Objectives Targeted therapies have markedly improved outcomes in chronic lymphocytic leukaemia (CLL), particularly among patients with TP53 alterations and unmutated IGHV. However, real‐world studies report persistent inequalities in access to optimal care.
Susana Esteves +7 more
wiley +1 more source

CYP2C19*2 and prognosis after an acute coronary syndrome: Insights from a Portuguese center

Revista Portuguesa de Cardiologia, 2012
Background: Clopidogrel requires oxidation dependent on the cytochrome P450 enzyme 2C19 (CYP2C19) to form its active metabolite. The importance of loss-of-function alleles (particularly CYP2C19*2, 681G>A) in poor platelet response to clopidogrel is well ...
Rogério Teixeira +12 more
doaj +1 more source

Allergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI Guidelines—2024–2025 Revision: Part I—Guidelines on Intranasal Treatments

Allergy, Volume 81, Issue 4, Page 954-976, April 2026.
ABSTRACT Background Allergic rhinitis (AR) impacts quality of life, work and school productivity. Over the last years, an important body of evidence resulting from mHealth data has led to a better understanding of AR. Such advances have motivated an EAACI‐endorsed update of the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines (ARIA 2024 ...
Bernardo Sousa‐Pinto +252 more
wiley +1 more source

Mortality is higher in patients with leptomeningeal metastasis in spinal cord tumors

Arquivos de Neuro-Psiquiatria, 2013
Spinal cord tumors are a rare neoplasm of the central nervous system (CNS). The occurrence of metastases is related to poor prognosis. The authors analyzed one series of metastasis cases and their associated mortality.
Ricardo de Amoreira Gepp +3 more
doaj

Violence Against Women, Mother–Infant Bond and Child Behaviour: An Exploratory Path Analysis at IVAPSA Cohort

Child: Care, Health and Development, Volume 52, Issue 2, March 2026.
ABSTRACT Background Violence experienced by women has serious consequences for maternal and child health, generating short‐ and long‐term damage. Objective The aim of this study was to evaluate the relation between violence experienced by women and the mother–child bond in the first 6 months after childbirth and on the child's mental health at ...
Viviane Costa de Souza Buriol +6 more
wiley +1 more source

Ressonância magnética cardíaca de perfusão em stress: a experiência de um centro nacional

Revista Portuguesa de Cardiologia, 2013
Resumo: Introdução e objectivos: A isquémia do miocárdio pode ser avaliada através da ressonância magnética de perfusão (RMp). O objetivo do trabalho foi avaliar o uso clínico da RMp no estudo da doença cardíaca isquémica (DCI).
Paulo Donato +5 more
doaj +1 more source

Quality of Life in Patients With Variant Syndromes of Autoimmune Liver Diseases—A Cross‐Sectional Multicentre Study

Liver International, Volume 46, Issue 3, March 2026.
ABSTRACT Background & Aims Primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH) go along with reduced health‐related quality of life (HRQOL). Variant syndromes, that is, conditions with features of both PBC/PSC and AIH, are associated with higher clinical complexity and worse prognosis. Studies on HRQOL
Natalie Uhlenbusch +34 more
wiley +1 more source

Revising the ABIDE MCI to dementia prediction model for automated cerebrospinal fluid assays

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Automated cerebrospinal fluid (CSF) biomarker assays have largely replaced manual immunoassays for measuring amyloid pathology in CSF. We refitted and validated the ABIDE model, predicting progression from mild cognitive impairment (MCI) to dementia, with CSF measurements from the automated Elecsys platform.
Pieter J. van der Veere +38 more
wiley +1 more source

Estratégias de retenção de profissionais de enfermagem nos hospitais: protocolo de scoping review

Revista de Enfermagem Referência, 2019
Enquadramento: A rotatividade de enfermagem tem impacto na qualidade do cuidado, na segurança do paciente e na produtividade dos hospitais. Objetivo: Mapear as estratégias de retenção do pessoal de enfermagem nos hospitais.
Letícia Helena do Nascimento +3 more
doaj +1 more source

Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI 2024–2025 Guidelines: From Evidence‐to‐Decision Frameworks to Digitalised Shared Decision‐Making Algorithms

Allergy, Volume 81, Issue 2, Page 427-453, February 2026.
The Allergic Rhinitis and its Impact on Asthma (ARIA) group is working on the 2024–2025 update of its guidelines for the management of allergic rhinitis (ARIA 2024–2025). The ARIA 2024–2025‐EAACI guidelines will follow GRADE methodology and will incorporate evidence from different sources, including systematic reviews and meta‐analyses, mHealth data ...
Jean Bousquet +230 more
wiley +1 more source

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