Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi +4 more
wiley +1 more source
Serogroup characterisation, co-pathogen causality, and environmental surveillance gaps in a cross-sectional study of Legionella pneumophila in hospital-acquired pneumonia. [PDF]
Mahashabde ML +2 more
europepmc +1 more source
Abstract Background Safe and timely nasogastric tube (NGT) placement is essential for effective enteral nutrition delivery in critically ill patients. Electromagnetic‐guided systems has been shown to improve placement accuracy and may reduce delays from confirmatory imaging, but evidence on how nurses acquire competence with this technology remains ...
Kazunao Mori +15 more
wiley +1 more source
The effectiveness of intravenous (IV) to oral (PO) antibiotic switch (IVOS) interventions in managing community- and hospital-acquired pneumonia-a systematic review. [PDF]
Obed-Arthur N, Lim RHM, Dunsmure L.
europepmc +1 more source
Abstract Background Efgartigimod disrupts the recycling of pathogenic IgG autoantibodies and may represent a candidate therapy for autoimmune encephalitis. This real‐world study evaluated the clinical efficacy, safety, and impact of efgartigimod on brain inflammation.
Huanyu Meng +12 more
wiley +1 more source
From plan to practice: a structured report on implementation strategies for preventing non-ventilator hospital-acquired pneumonia (nvHAP). [PDF]
Wolfensberger A +3 more
europepmc +1 more source
CHARGE Syndrome: What an Otolaryngologist Should Know—A Systematic Review and Meta‐Analysis
Abstract Objective To synthesize the prevalence of otolaryngologic manifestations in CHARGE syndrome (CS) to support otolaryngologists in delivering comprehensive management. Data Sources PubMed/MEDLINE, Embase, and Google Scholar were searched for English‐ and French‐language studies published from January 1980 through January 2025.
Camille Caron +5 more
wiley +1 more source
Comparative Genomic Analysis of <i>Pseudomonas aeruginosa</i> Isolates from Community-Acquired and Hospital-Acquired Pneumonia. [PDF]
Yang F +11 more
europepmc +1 more source
Safety and Efficacy of the Versius Surgical System in Transoral Robotic Surgery: A Prospective Study
Abstract Objective To evaluate the safety and feasibility of the Versius surgical robotic system for transoral robotic surgery in benign and malignant head and neck indications. Study Design Open‐label, prospective, single‐arm, phase II clinical trial. Setting Liverpool Head and Neck Centre, United Kingdom. Methods Between December 2023 and March 2025,
Jason C. Fleming +11 more
wiley +1 more source
Effect of traumatic brain injury on the trough concentration of linezolid in patients with hospital-acquired pneumonia. [PDF]
Zhang Y +9 more
europepmc +1 more source

