Results 191 to 200 of about 41,230 (241)

RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy. [PDF]

open access: yesAdv Sci (Weinh)
Wu P   +12 more
europepmc   +1 more source

Tumour‐Derived Extracellular Vesicles Reprogramme Tumour‐Associated Macrophages Into Immunosuppressive Phenotype via NOD1 Signalling in Clear Cell Renal Cell Carcinoma

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Clear cell renal cell carcinoma (ccRCC)‐derived extracellular vesicles (EVs) play a pivotal role in myeloid cell differentiation toward immunosuppressive phenotypes, yet the underlying mechanisms remain poorly understood. Through integrated single‐nucleus RNA sequencing, EV proteomics, and phenotype validation, we identified NOD1, a pattern ...
Xiu‐wu Pan   +26 more
wiley   +1 more source

Luspatercept in Transfusion‐Dependent Thalassemia With Red Blood Cell Antibodies: A Case Series

open access: yeseJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Red blood cell (RBC) antibodies complicate transfusion support in transfusion‐dependent thalassemia (TDT), and data on luspatercept in this setting remain limited. We retrospectively reviewed seven adults with TDT and RBC antibodies treated with luspatercept at Srinagarind Hospital from January 2025 to January 2026.
Nattiya Teawtrakul
wiley   +1 more source

Defining hotspot for estimation of Ki-67 proliferation index of neuroendocrine tumors: QuPath algorithm vs. manual assessment. [PDF]

open access: yesJ Pathol Inform
Oganesyan R   +9 more
europepmc   +1 more source

CMAISE: Establishing the Longitudinal Multi‐Omics Cohort for Sepsis Precision Medicine

open access: yesMed Research, Volume 2, Issue 2, Page 397-404, June 2026.
ABSTRACT Sepsis remains a leading cause of mortality worldwide due to its profound biological heterogeneity. While multi‐omics approaches offer promise for precision medicine, existing datasets often lack longitudinal granularity or comprehensive clinical integration. We present the Chinese Multi‐omics Advances In Sepsis (CMAISE) cohort, a prospective,
Jie Yang   +36 more
wiley   +1 more source

Distinct Proteomic Signatures Driving Progression of Sarcopenia: A Longitudinal Multicohort Study. [PDF]

open access: yesJ Cachexia Sarcopenia Muscle
Kong SH   +8 more
europepmc   +1 more source

ω‐3PUFAs Inhibit Gallbladder Cancer Through Enhancing STK31 Methylation

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 11, 15 June 2026.
ABSTRACT Gallbladder cancer (GBC) is an aggressive malignancy with limited treatment options. ω‐3PUFAs have known anticancer activity, but their role in GBC remains unclear. The anti‐GBC effects of ω‐3PUFAs (DHA/EPA) were evaluated using in vitro assays and mouse xenograft models.
Shuang‐Xing Li   +16 more
wiley   +1 more source

A preliminary study developing a scoring model incorporating fibrinogen-like protein 2 for predicting glucocorticoid resistance in thyroid eye disease. [PDF]

open access: yesThyroid Res
Matsuzawa K   +11 more
europepmc   +1 more source

Waste Management Policies, Practices, and Public Health Outcomes in Developing Countries: A Systematic Review and Meta‐Analysis

open access: yesPublic Health Challenges, Volume 5, Issue 2, June 2026.
Unsanitary waste practices in developing countries increase disease risks by 2.1–3.1 times. This review demonstrates that integrating waste pickers, enforcing policies, and investing in circular systems can reduce health burdens by 30–50%, offering a clear path toward sustainable urban health.
Ashenafi Woldemichael Woime
wiley   +1 more source

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