RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy. [PDF]
Wu P +12 more
europepmc +1 more source
ABSTRACT Clear cell renal cell carcinoma (ccRCC)‐derived extracellular vesicles (EVs) play a pivotal role in myeloid cell differentiation toward immunosuppressive phenotypes, yet the underlying mechanisms remain poorly understood. Through integrated single‐nucleus RNA sequencing, EV proteomics, and phenotype validation, we identified NOD1, a pattern ...
Xiu‐wu Pan +26 more
wiley +1 more source
Acute arterial occlusion following inadvertent infusion of ferric hydroxide sacarate (Noripurum®) into the radial artery: case report. [PDF]
Fernandes DCM +4 more
europepmc +1 more source
Luspatercept in Transfusion‐Dependent Thalassemia With Red Blood Cell Antibodies: A Case Series
ABSTRACT Red blood cell (RBC) antibodies complicate transfusion support in transfusion‐dependent thalassemia (TDT), and data on luspatercept in this setting remain limited. We retrospectively reviewed seven adults with TDT and RBC antibodies treated with luspatercept at Srinagarind Hospital from January 2025 to January 2026.
Nattiya Teawtrakul
wiley +1 more source
Defining hotspot for estimation of Ki-67 proliferation index of neuroendocrine tumors: QuPath algorithm vs. manual assessment. [PDF]
Oganesyan R +9 more
europepmc +1 more source
CMAISE: Establishing the Longitudinal Multi‐Omics Cohort for Sepsis Precision Medicine
ABSTRACT Sepsis remains a leading cause of mortality worldwide due to its profound biological heterogeneity. While multi‐omics approaches offer promise for precision medicine, existing datasets often lack longitudinal granularity or comprehensive clinical integration. We present the Chinese Multi‐omics Advances In Sepsis (CMAISE) cohort, a prospective,
Jie Yang +36 more
wiley +1 more source
Distinct Proteomic Signatures Driving Progression of Sarcopenia: A Longitudinal Multicohort Study. [PDF]
Kong SH +8 more
europepmc +1 more source
ω‐3PUFAs Inhibit Gallbladder Cancer Through Enhancing STK31 Methylation
ABSTRACT Gallbladder cancer (GBC) is an aggressive malignancy with limited treatment options. ω‐3PUFAs have known anticancer activity, but their role in GBC remains unclear. The anti‐GBC effects of ω‐3PUFAs (DHA/EPA) were evaluated using in vitro assays and mouse xenograft models.
Shuang‐Xing Li +16 more
wiley +1 more source
A preliminary study developing a scoring model incorporating fibrinogen-like protein 2 for predicting glucocorticoid resistance in thyroid eye disease. [PDF]
Matsuzawa K +11 more
europepmc +1 more source
Unsanitary waste practices in developing countries increase disease risks by 2.1–3.1 times. This review demonstrates that integrating waste pickers, enforcing policies, and investing in circular systems can reduce health burdens by 30–50%, offering a clear path toward sustainable urban health.
Ashenafi Woldemichael Woime
wiley +1 more source

