Results 201 to 210 of about 14,035,857 (361)

13º Jornada do Serviço de Educação Física e Terapia Ocupacional

open access: yesClinical and Biomedical Research
A Jornada do Serviço de Educação Física e Terapia Ocupacional (SEFTO) do Hospital de Clínicas de Porto Alegre é um evento tradicional, que geralmente ocorre a cada 4 anos, que em razão da pandemia somente pode ser retomada em 2024.
Hospital de Clínicas de Porto Alegre
doaj   +2 more sources

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

open access: yesFEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang   +11 more
wiley   +1 more source

An Interactive Decision-Support Dashboard for Optimal Hospital Capacity Management [PDF]

open access: yesarXiv
Data-driven optimization models have the potential to significantly improve hospital capacity management, particularly during demand surges, when effective allocation of capacity is most critical and challenging. However, integrating models into existing processes in a way that provides value requires recognizing that hospital administrators are ...
arxiv  

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

House Keeping in Hospitals

open access: bronze, 1953
Rajammal P. Devdas
openalex   +1 more source

The Hybrid Hospital: Balancing On-Site and Remote Hospitalization [PDF]

open access: yesarXiv
Hybrid hospitals offer on-site and remote hospitalization through telemedicine. These new healthcare models require novel operational policies to balance costs, efficiency, and patient well-being. Our study addresses two first-order questions: (i) how to direct patient admission and call-in based on individual characteristics and proximity and (ii) how
arxiv  

Tryptophan‐sensing receptor GPR142 expression levels are directly regulated by proinflammatory cytokines in ghrelin‐producing cells

open access: yesFEBS Open Bio, EarlyView.
GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda   +15 more
wiley   +1 more source

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