Results 201 to 210 of about 8,290,010 (315)

Extreme heat and cause-specific risk of hospital admission in the adult population in England: a case time series analysis. [PDF]

BMJ Open
Flower G, Cole R, Libardi AC, Mieiro L, Quint JK, Gasparrini A, Masselot P.   +6 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

An updated systematic review of the impact of volume of surgery and specialization in Norwood procedure. [PDF]

BMC Pediatr
Pachanov A, Zhang Z, Munschek S, Asfour B, Mathes T, Pieper D.   +5 more
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Preoperative Risk Evaluation for Cancer Treatment (PREdiCT): protocol for an international cohort study evaluating a trimodal screening tool to predict outcomes following gastrointestinal cancer surgery. [PDF]

BMJ Open
Reeves J, Koh C, Alexander K, Solomon M, Karunaratne S, Petridis A, Carey S, Dhillon H, White K, Pillinger N, Gillis C, Hirst N, Shadid Z, Rahman MI, Boden I, Mahoney A, Woodfield J, Vagg D, De Boer HD, Sutton P, Pereira L, Drummond-Lage AP, Mcloughlin S, Alvarez A, Pirie K, Hii MW, Suliman A, Uçaner B, Schizas D, Nassim K, Albatool R, Ali K, Triantafyllou T, Styliana A, Merlini I, Van Daele E, Mulita F, Bell M, Martinez-Palli G, Koch C, Falconi M, Garmanova T, Deng N, Tirelli F, Lubbers T, Chwat C, Costales A, Hanna NM, Petrova A, Khamees A, Beard D, Granger CL, PREdiCT Study Investigators, Steffens D.   +53 more
europepmc   +1 more source

Photos of Modbury Hospital and Staff Members

Faded colour photos of Modbury Hospital and various staff members, including a Christmas party and a celebratory ...
Modbury Hospital
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Retraction Note: Flavokawain C suppresses nephroblastoma growth by inducing autophagy-mediated downregulation of FABP4 via AMPK/mTOR pathway. [PDF]

Sci Rep
Liu Q, Tian Y, Li G, Zhang S, Gao Y, Ma X, Su Z, Fan W, Li H.   +8 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Quality education initiative to reduce pressure ulcers in high-risk-admitted patients in low-resource settings. [PDF]

BMJ Open Qual
Khattak AF, Hussain S, Ahmad B, Khattak M, Afridi WV, Khan B.   +5 more
europepmc   +1 more source