Results 261 to 270 of about 12,173,986 (325)

Functional Connectivity Associations With Markers of Disease Progression in GRN Pathogenic Variant Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autosomal dominant progranulin (GRN) pathogenic variants are a genetic cause of frontotemporal lobar degeneration. Though clinical trials for GRN‐related therapies are underway, there is an unmet need for biomarkers that can predict symptom onset and track disease progression.
Taru M. Flagan, Stephanie A. Chu, Suvi Häkkinen, Liwen Zhang, David McFall, Jonathan D. Rohrer, Jesse A. Brown, Alex J. Lee, Kristen Fernhoff, Lorenzo Pasquini, Katherine P. Rankin, Maria Luisa Mandelli, Maria Luisa Gorno‐Tempini, Jennifer S. Yokoyama, Virginia E. Sturm, Brian Appleby, Bradford C. Dickerson, Kimiko Domoto‐Reilly, Tatiana Foroud, Daniel H. Geschwind, Nupur Ghoshal, Neill R. Graff‐Radford, Ging‐Yuek Robin Hsiung, Eric J. Huang, Edward Huey, Kejal Kantarci, Irene Litvan, Ian R. Mackenzie, Mario F. Mendez, Chiadi U. Onyike, Leonard Petrucelli, Eliana Marisa Ramos, Erik D. Roberson, Julio C. Rojas, Maria Carmela Tartaglia, Arthur W. Toga, Sandra Weintraub, Leah K. Forsberg, Hilary W. Heuer, Brad F. Boeve, Adam L. Boxer, Howard J. Rosen, Bruce L. Miller, Fermin Moreno, William W. Seeley, Suzee E. Lee, on behalf of the ALLFTD Consortium   +46 more
wiley   +1 more source

Retraction: Multidisciplinary Approaches to Limb Salvage in Traumatic Extremity Injuries From Emergency Triage to Definitive Vascular, Orthopedic, and Reconstructive Surgery: A Systematic Review. [PDF]

Cureus
Issa Youssouf N, Khan HA, Ahmed Osman Mohamed A, Bahaa Aboelsebaa Othman M, Ismail MHF, Hassan AA, Alkhazendar AH, H J Alkhazendar J, Zehra M, Aakash D.   +9 more
europepmc   +1 more source

Practice Recommendations for Genetic Testing of Ataxias

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Over the past decade, significant advances in genetic testing for ataxia have improved diagnostic accuracy, informed clinical trial eligibility, guided treatment decisions, and enabled cascade testing of at‐risk relatives. While guidance exists for other neurogenetic conditions, there are no standardized guidelines on genetic ...
Sharan R. Srinivasan, Amy D. Mook, Michelle Rochman, Jin Yun Helen Chen, Weiyi Mu, George R. Wilmot, Liana S. Rosenthal, Wendy R. Uhlmann   +7 more
wiley   +1 more source

Critical care outcome prediction equation model, version 7. [PDF]

Crit Care Resusc
Duke GJ, Hirth S, Santamaria JD, Shann F, Pilcher D, Oberender F, Knott C, Moran J.   +7 more
europepmc   +1 more source

REPORT TO THE LANG CLINICAL RESEARCH COMMITTEE, ROYAL LONDON OPHTHALMIC HOSPITAL: A BILATERAL CHRONIC AFFECTION OF THE ENDOTHELIAL FACE OF THE CORNEA OF ELDERLY PERSONS WITH AN ACCOUNT OF THE TECHNICAL AND CLINICAL PRINCIPLES OF ITS SLIT-LAMP OBSERVATION

, 1924
Barbara J. Graves
openalex   +1 more source

Caution - suicidal patient note

, 2015
Deva Hospital Chester
core  

Cognitive Impairment in Multiple Sclerosis: The Role of Clinical and Sociodemographic Factors ‐ A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment (CI) affects the quality of life in multiple sclerosis (MS). Identifying influencing factors is key to improving CI monitoring. This systematic review and meta‐analysis examines clinical and sociodemographic variables impacting the cognitive screening Symbol Digit Modalities Test (SDMT) performance across MS ...
Katalin Lugosi, Marie A. Engh, Tamás Kói, Zsolt Molnár, Gábor Csukly, Klaudia Horváth, Emma Hargitai, Péter Hegyi, Zsolt Mezei   +8 more
wiley   +1 more source

Dyadic Coping of NMOSD and MOGAD patients and their partners: a sociological and psychological examination of strategies (CoMMOnsense-Study). [PDF]

BMJ Neurol Open
Walz A, Tkachenko D, Hümmert MW, Schindler P, Bellmann-Strobl J, Paul F, Aktas O, Ringelstein M, Giglhuber K, Zappe C, Leypoldt F, Lüssi F, Ayzenberg I, Schwake C, Wallwitz U, Kretschmer JR, Bütow F, Angstwurm K, Husseini L, Häußler V, Then Bergh F, Haarmann A, Lehrieder D, Warnke C, Kümpfel T, Engels D, Zimmermann T, Trebst C, Neuromyelitis Optica Study Group (NEMOS).   +28 more
europepmc   +1 more source

Art. VIII.—Notice of a remarkable Hospital for Animals at Surat [PDF]

Alex Burnes
openalex   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source