Results 41 to 50 of about 11,396,055 (313)

Cangrelor en el intervencionismo coronario percutáneo: una «nueva» arma del arsenal terapéutico antitrombótico

open access: yesREC: Interventional Cardiology, 2020
Durante la segunda mitad de 2019 se inició en nuestro país la comercialización del cangrelor, un «nuevo» antiagregante plaquetario con características farmacológicas singulares que lo hacen atractivo para determinadas situaciones clínicas en el contexto ...
José Luis Ferreiro   +1 more
doaj   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

Does hospital cooperation increase the quality of healthcare? [PDF]

open access: yesarXiv, 2019
Motivated by reasons such as altruism, managers from different hospitals may engage in cooperative behaviours, which shape the networked healthcare economy. In this paper we study the determinants of hospital cooperation and its association with the quality delivered by hospitals, using Italian administrative data.
arxiv  

VIEW: a framework for organization level interactive record linkage to support reproducible data science [PDF]

open access: yesarXiv, 2021
Objective: To design and evaluate a general framework for interactive record linkage using a convenient algorithm combined with tractable Human Intelligent Tasks (HITs; i.e. micro tasks requiring human judgment) that can support reproducible data science.
arxiv  

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Recognition and Ranking Critical Success Factors of Business Intelligence in Hospitals -- Case Study: Hasheminejad Hospital [PDF]

open access: yes, 2014
Business Intelligence, not as a tool of a product but as a new approach is propounded in organizations to make tough decisions in business as shortly as possible. Hospital managers often need business intelligence in their fiscal, operational, and clinical reports and indices. The main goal of recognition and ranking CSF is implementation of a business
arxiv   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

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