Results 71 to 80 of about 6,573,800 (334)

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Conferencias anatomoclínicas: caso no. veintidos

Revista de la Facultad de Medicina, 1955
E. A. v de C. 52 años. Ciudad de origen: Girardot. Ciudad de procedencia: Bogotá. Servicio del Profesor Guerrero Izquierdo. NOTA CLINICA: La enferma ingresa al Servicio de Urgencia el 13 de mayo de 1952 a las 5 :30 p. m.
San Juan de Dios Hospital
doaj  

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source

Conferencias anatomoclínicas: caso no. veintitres

Revista de la Facultad de Medicina, 1955
Se hace una revisión de un caso clínico presentado en el Hospital San Juan de Dios, Bogotá.
Hospital San Juan de Dios
doaj  

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

NOTES ON MICROSCOPY OF THE LIVING EYE: Report of the Lang Clinical Research Scholarship, Royal London Ophthalmic Hospital [PDF]

, 1924
B. Graves
openalex   +1 more source

Conferencias anatomoclínicas: caso no. diez y ocho

Revista de la Facultad de Medicina, 1955
L. M. B. 16 años. Ciudad de Origen y Procedencia: Susa. Servicio del Prof. Manuel José Luque. NOTA CLINICA: La enferma ingresa al Servicio de Clínica Quirúrgica el 18 de enero de 1952, por presentar un bocio.
San Juan de Dios Hospital
doaj  

Culdoscopia para infertilidad

Revista Colombiana de Obstetricia y Ginecología, 1960
Los autnres reportan sobre 203 culdoscopias practicadas entre Diciembre de 1948 y Julío de 1958 en pacientes que consultaron por problemas de infertilidad.
H. L. Riva, Walter Reed Army Hospital
doaj   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Technology in Hospitality Industry: Prospects and Challenges [PDF]

arXiv, 2017
The leisure and hospitality industry is one of the driving forces of the global economy. The widespread adoption of new technologies in this industry over recent years has fundamentally reshaped the way in which services are provided and received. In this paper, we explore some of the state-of-the-art technologies currently employed in the hospitality ...
arxiv