Results 71 to 80 of about 15,847,430 (379)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Conferencias anatomoclínicas: caso no. veintiocho

Revista de la Facultad de Medicina, 1956
Se hace una revisión de un caso clínico presentado en el Hospital San Juan de Dios, Bogotá.
San Juan de Dios Hospital
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Study on the Influence and Mechanism of Resveratrol on Cognitive Impairment in Chronic Kidney Disease Rats Through Regulating Gut Microbiota and the TLR4/NFκB Pathway

Journal of Inflammation Research
Binbin Shao,1 Yanfei Nong,1 Yongshuang Lin,2 Yan Meng,1 Yi Zhou,1 Meiying Huang,3 Feifan Huang,3 Jie Wang3 1Graduate School, Youjiang Medical University for Nationalities, Baise, Guangxi, 533000, People’s Republic of China; 2The First Affiliated Hospital
Shao B, Nong Y, Lin Y, Meng Y, Zhou Y, Huang M, Huang F, Wang J   +7 more
doaj  

Conferencias anatomoclínicas: caso no. veinte

Revista de la Facultad de Medicina, 1955
S. L. 16 años. Ciudad de origen y procedencia: San Martín. Servicio del Prof. Luis María Salgar. NOTA CLINICA: La paciente ingresa al Servicio de Clínica Médica el 25 de Octubre de 1951 con disnea de esfuerzo y de decúbito, tos con expectoración ...
San Juan de Dios Hospital
doaj  

Annual Incidence of Adult and Pediatric In-Hospital Cardiac Arrest in the United States

Circulation. Cardiovascular Quality and Outcomes, 2019
BACKGROUND Previous incidence estimates may no longer reflect the current public health burden of cardiac arrest in hospitalized adult and pediatric patients across the United States.
M. Holmberg, Catherine E. Ross, G. Fitzmaurice, P. Chan, J. Duval-Arnould, A. Grossestreuer, T. Yankama, M. Donnino, L. Andersen   +8 more
semanticscholar   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

, 1976
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1125/thumbnail ...

core   +4 more sources

Dual Effects of Sodium Houttuyfonate Against Acute Rhinosinusitis: Antibacterial Action and Epithelial Barrier Repair Through the p38 MAPK/ERK Pathway

Journal of Inflammation Research
Yang Fang, Huixia Zhou, WeiYi Li, Lu Bai, Xinchen Sun, KaiYuan He, Shanshan Xue, Yongjun Wu Department of Otolaryngology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210029, People’s Republic of ChinaCorrespondence ...
Fang Y, Zhou H, Li W, Bai L, Sun X, He K, Xue S, Wu Y   +7 more
doaj