Results 101 to 110 of about 439,843 (306)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

From Screening to Strategy: Targeted Carbapenem‐Resistant Enterobacteriaceae (CRE) Infection Prediction After Endoscopic Retrograde Cholangiopancreatography (ERCP)

Infection and Drug Resistance
Jundi Wang,1 Kaisheng Su,1 Shuying Wang,2,3 Yanfei Yang2 1Department of Rheumatology and Immunology, Hangzhou First People’s Hospital Affiliated of Westlake University School of Medicine, Hangzhou, Zhejiang, People’s Republic of China; 2Department of ...
Wang J, Su K, Wang S, Yang Y
doaj  

Economics and preventing healthcare acquired infection

, 2009
The evolution of organisms that cause healthcare acquired infections (HAI) puts extra stress on hospitals already struggling with rising costs and demands for greater productivity and cost containment.
Halton, Kate A., Graves, Nicholas, Jarvis, William   +2 more
core   +1 more source

The effect of triclosan coated sutures on rate of Surgical Site Infection after hip and knee replacement : a protocol for a double-blind randomised controlled trial [PDF]

, 2014
Background: 187,000 hip and knee joint replacements are performed every year in the National Health Service (NHS). One of the commonest complications is surgical site infection (SSI), and this represents a significant burden in terms of patient ...
Reed, Mike R., Parsons, Nicholas R., Andrew P Sprowson, Roland Pratt, Asaad, Seif, Kevin Emmerson, Seif Asaad, Scott Muller, Cyrus D Jensen, Nick Parsons, Pratt, Roland, Muller, Scott, Mike R Reed, Ian Carluke, Paul Partington, Jensen, Cyrus D., Partington, Paul, Carluke, Ian, Sprowson, Andrew P., Emmerson, Kevin   +19 more
core   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Analysis of Hospital-Acquired Infections in a Chinese Specialized Rehabilitation Hospital: A Five-Year Surveillance Study (2020-2024)

Infection and Drug Resistance
Qianfeng Li,1 Dong Wang,1 Hanyuan Fan2 1Department of Geriatric Rehabilitation, Shenzhen Dapeng New District Nan’ao People’s Hospital, Shenzhen, People’s Republic of China; 2Hospital-Acquired Infection Control department, Shenzhen Dapeng New District Nan’
Li Q, Wang D, Fan H
doaj  

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Bacteriology of hospital-acquired infection and antibiotic resistance in a hospital university of Bushehr Port Fatemeh Zahra (s) in 2002-2003

Iranian South Medical Journal, 2005
Nosocomial infection is an increasing problem. The global problem of antimicrobial resistance is particularly pressing in developing countries, where the infectious disease burden is high and cost constraints prevent the widespread application of newer ...
Katayoon Vahdat, Roohollah Rezaee, Omid Gharibi   +2 more
doaj