Results 61 to 70 of about 4,912,407 (280)
Invasive Bacterial Co-infection in African Children with Plasmodium falciparum Malaria: A Systematic Review. [PDF]
, 2014 Severe malaria remains a major cause of pediatric hospital admission across Africa. Invasive bacterial infection (IBI) is a recognized complication of Plasmodium falciparum malaria, resulting in a substantially worse outcome.
Maitland, Kathryn +4 more
core +2 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Antimicrobial Resistance and Infection Control, 2020 Background Effective infection prevention and control strategies require reliable data describing the epidemiology of hospital acquired infections (HAIs), and this is currently lacking in Nigeria.
Usman Abubakar
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Application of agent-based simulation to the modelling and management of hospital-acquired infections [PDF]
Hospital-acquired infections (HAIs) are a big threat to the well-being of patients and place a heavy burden on hospital resources. The thesis provides the first attempt to apply agent-based simulation (ABS) to describe the transmission dynamics and ...
Meng, Yang
core
Probiotics for pediatric diarrhea and constipation: an umbrella meta-analysis
BMC PediatricsBackground The current evidence regarding the impact of probiotics on diarrhea and constipation outcomes in children is inconclusive. This umbrella review of systematic reviews and meta-analyses aims to deliver a comprehensive and conclusive summary of ...
Le Chen +4 more
doaj +1 more source
The Professional Medical Journal, 2010 Nosocomial infections may be defined as the infections which develop within hospital. There are different types of microorganisms which are involved along with other agents for the spread of these infections. Knowledge about the spread and prevention of these infections is the basic step for control.
SHAZIA QAYYUM +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Monitoring Quality of Care Through Linkage of Administrative Data: National Trends in Bloodstream Infection in U.K. PICUs 2003-2012. [PDF]
, 2015 OBJECTIVES Interventions to reduce hospital-acquired bloodstream infection have succeeded in reducing rates in U.S. PICUs, but there is a lack of evidence for the impact of similar interventions in the United Kingdom.
Tibby, Shane M +13 more
core +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source