Results 111 to 120 of about 2,550,559 (379)

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Three- versus four-factor prothrombin complex concentrate for the reversal of warfarin-induced bleeding [PDF]

open access: yes, 2018
Objective: The objective of this study was to evaluate the effectiveness of 3-factor prothrombin complex concentrate (3F-PCC) compared to 4-factor PCC (4F-PCC) in warfarin-associated bleeding. Methods: This multicenter, retrospective, cohort study
Abraham, Prasad   +6 more
core   +1 more source

Administración eficiente del capital humano y efectividad institucional de los hospitales

open access: yesRevista GICOS, 2023
La administración eficiente del capital humano y la efectividad institucional de los centros hospitalarios es fundamental para la efectividad institucional.
Carmen Cruz-Chagmani   +3 more
doaj  

Aspectos gerais e número de etapas do sistema de medicação de quatro hospitais brasileiros Aspectos generales y número de etapas del sistema de medicación en cuatro hospitales brasileños General aspects and number of phases of the medication system in four brazilian hospitals

open access: yesRevista Latino-Americana de Enfermagem, 2004
Essa investigação identificou e analisou o sistema de medicação de 04 hospitais universitários, localizados nas cidades de Recife, Ribeirão Preto, Goiânia e São Paulo, após a aprovação nos Comitês de Ética em Pesquisa e da autorização da direção dos ...
Silvia Helena de Bortoli Cassiani   +4 more
doaj   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Verbal Abuse of Pediatric Nurses by Patients and Families [PDF]

open access: yes, 2013
Objective: The purpose of this study was to determine the extent to which nurses practicing in a pediatric hospital encounter verbal abuse by patients and families and their reactions to this abuse.
Berger, Jill   +4 more
core   +1 more source

The conflict in the nurse managing exercise in hospital context – preview note.

open access: yesOnline Brazilian Journal of Nursing, 2008
This work is the result of a masters dissertation project developed in Post-Graduation Program in Nursing from the Federal University of Santa Maria (UFSM).
Soeli Teresinha Guerra   +1 more
doaj  

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Treatment of Anaphylaxis in Adults: A Questionnaire Survey [PDF]

open access: yes, 2009
Objective: To identify the medications that medical students, interns and casualty medical officers are likely to prescribe when treating an adult patient with anaphylaxis, and to ascertain the dose and route of administration of adrenaline they would ...
Adiga, Shalini, Bairy, KL, Nayak, Veena
core   +1 more source

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