Results 171 to 180 of about 2,780,282 (316)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Modeling nurses' acceptance of bar coded medication administration technology at a pediatric hospital [PDF]

, 2012
Richard Holden, Roger Brown, Matthew C. Scanlon, Ben‐Tzion Karsh   +3 more
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Identifying barriers to the administration of pre-hospital analgesia to adult trauma patients by UK paramedics: a qualitative interview study

, 2019
Adam Smith, Jeremy Henning
openalex   +1 more source

The administration of dextrose during in-hospital cardiac arrest is associated with increased mortality and neurologic morbidity [PDF]

, 2015
Teng J. Peng, Lars W. Andersen, Brian Z. Saindon, Tyler Giberson, Won Young Kim, Katherine M. Berg, Victor Novack, Michael W. Donnino   +7 more
openalex   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Adopt-a-Hospital Project: An instructional tool for hospital administration

, 2016
Asa B. Wilson
openalex   +2 more sources

ADMINISTRATION OF FRESH FROZEN PLASMA IN ACE INHIBITOR-INDUCED ANGIOEDEMA DOES NOT REDUCE ICU OR HOSPITAL LENGTH OF STAY [PDF]

, 2022
J. BEAUDIN, M. COLANCECCO, J. DARGIN, C. HANSEN   +3 more
openalex   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Prevalence and Outcomes Associated with Idarucizumab Administration in Trauma Patients on Preinjury Dabigatran Therapy: Analyzing Clinical Utilization in 942 Patients from 74 Hospitals [PDF]

Rebecca Moore, Ransom J. Wyse, J. Bruce Jacobs, Samir M. Fakhry, Nina Y. Wilson, Jeneva M. Garland   +5 more
openalex   +1 more source