Results 291 to 300 of about 2,550,559 (379)
The PVA‐GA hydrogel is formed through hydrogen bonding between PVA hydroxyl groups and GA galloyl units, enabling sustainable GA release and its extended biological activity. The hydrogel scavenges ROS to reduce oxidative stress, preventing mitochondrial damage from excessive ROS, mitigating hADSC senescence, and preserving VEGF secretion, offering a ...
Yiduo Zhou+11 more
wiley +1 more source
Coagulopathy as a predictor of the effectiveness of tranexamic acid in severe blunt trauma: a multicenter retrospective study. [PDF]
Takahashi Y+5 more
europepmc +1 more source
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia+7 more
wiley +1 more source
Time to administer polymyxin B hemoperfusion and hemodynamics in patients with septic shock requiring high-dose norepinephrine: a predetermined analysis of a prospective cohort study. [PDF]
Miyamoto K+20 more
europepmc +1 more source
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche+16 more
wiley +1 more source
Prevalence of medication administration errors and its determinants among nurses in Ethiopia: a systematic review and meta-analysis. [PDF]
Wudu MA+3 more
europepmc +1 more source
Reinforced Polymer–Nanoparticle Hydrogels for Subcutaneous and Sustained Delivery of Trastuzumab
Biologic therapy development is rapidly accelerating, requiring extended delivery formulation strategies. Supramolecular hydrogels and electrostatic complexation create subcutaneous depots that release clinically relevant trastuzumab doses in a controlled manner through simple component mixing without chemical modifications.
Giovanni Bovone+17 more
wiley +1 more source
Thiamine administration and in-hospital mortality in patients with traumatic brain injury: analysis of the MIMIC-IV database. [PDF]
Gao S, Zhu Z, Zheng W.
europepmc +1 more source