Results 81 to 90 of about 5,674,242 (278)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

INSTRUMENTOS ADMINISTRATIVOS: PERCEPÇÃO DE ENFERMEIROS DE UM HOSPITAL UNIVERSITÁRIO

open access: yesCogitare Enfermagem, 2010
Instrumentos administrativos são documentos que estruturam e normalizam uma instituição e/ou serviço. Opresente estudo, do tipo exploratório-descritivo, teve como objetivo investigar o conhecimento de enfermeiros sobre osinstrumentos administrativos e a ...
Laura Misue Matsuda   +4 more
doaj   +1 more source

Modbury Hospital aerial photos

open access: yes
Three photos showing Modbury Hospital from an aerial angle on the same sheet of ...
Modbury Hospital
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Modbury Hospital Cashier photo

open access: yes
Large Colour photo of a man talking to the cashier in the Modbury Hospital ...
Modbury Hospital
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Indicadores de qualidade utilizados no gerenciamento da assistência de enfermagem hospitalar [Healthcare quality indicators used in hospital nursing care management]

open access: yesRevista Enfermagem UERJ, 2016
Este estudo objetivou identificar a opinião de enfermeiros sobre indicadores de qualidade da assistência de enfermagem. Trata-se de uma pesquisa descritiva, transversal, de abordagem quantitativa, realizada em quatro hospitais de média e alta ...
Paloma de Souza Cavalcante   +3 more
doaj  

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