Results 31 to 40 of about 617,600 (335)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Perceived barriers and facilitators to breast-feeding support practices in hospitals and birthing facilities in the USA

open access: yesPublic Health Nutrition
Objective: The Baby-Friendly Hospital Initiative (BFHI) designation is known to increase breast-feeding rates in the USA. However, less is known about barriers and facilitators to breast-feeding support practices in BFHI hospitals and how they differ ...
Bee-Ah Kang   +2 more
doaj   +1 more source

HUBUNGAN FAKTOR DEMOGRAFI, PERIODE DAN LAMA KERJA DOKTER TERHADAP KETERLAMBATAN PENGISIAN RESUME MEDIS PASIEN BPJS DI RUANG RAWAT INAP RSAU DR. ESNAWAN ANTARIKSA

open access: yesJurnal Profesi Medika, 2017
More than 50% of the medical resume at airforce hospital (RSAU) were not returned in due time which caused claim verifcation delayed by social security administrator (BPJS).
Nia Nuraini   +2 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Barnes Hospital Record [PDF]

open access: yes, 1953
https://digitalcommons.wustl.edu/bjc_barnes_record/1077/thumbnail ...

core   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas   +7 more
wiley   +1 more source

Epidemiology of cancers in Lahore, Pakistan, 2010–2012: a cross-sectional study

open access: yesBMJ Open, 2016
Objectives To estimate the population-level cancer estimates for the Lahore district, which is part of the Punjab Cancer Registry (PCR), Pakistan.
Farhana Badar   +3 more
doaj   +1 more source

Barnes Hospital Bulletin [PDF]

open access: yes, 1984
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1221/thumbnail ...

core   +1 more source

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