Results 101 to 110 of about 62,417 (266)

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

open access: yesAdvanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue   +17 more
wiley   +1 more source

Micro‐Organ Chip Deciphers Tumor‐Derived G‐CSF as Remote Commander of Lung Pre‐Metastatic Niche via VEGFA‐KDR Cascade

open access: yesAdvanced Science, EarlyView.
Breast cancer reprograms the lung into a receptive pre‐metastatic niche via a novel G‐CSF–VEGFA–KDR signaling axis. Using a micro‐organ chip that enables contact‐independent coculture, this study uncovers how tumor‐secreted G‐CSF activates lung capillary KDR to drive angiogenesis and prime the soil for metastasis—without direct tumor contact.
Jingxin Zhang   +12 more
wiley   +1 more source

The level of propensity to outsource Study: Based on hospital services features by managers and staff perspective in hospitals Kavousi Z Abstract: of Shiraz University of Medical Science, 2010

open access: yesبیمارستان, 2012
Background: The inefficiency of financing health care in developing countries made led in manyhealth policy-makers to consider alternate means of service provisions. Outsourcing public financed health services in private sector organization is one of the
Z Kavousi   +5 more
doaj  

HOSPITAL ADMINISTRATION [PDF]

open access: yesAJN, American Journal of Nursing, 1923
openaire   +1 more source

Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action

open access: yesAdvanced Science, EarlyView.
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang   +27 more
wiley   +1 more source

Hospital governance accountability challenges in Iran: a qualitative study

open access: yesBMC Health Services Research
Introduction Hospital governance is crucial for ensuring the quality of care and patient safety. Despite numerous reforms in hospital governance accountability structures in Iran, some challenges persist.
Mohammad Ali Jalilvand   +2 more
doaj   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

open access: yesAdvanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang   +7 more
wiley   +1 more source

Proposing conceptual frameworks for prevention and management of workplace violence against healthcare workers in a Nigerian State

open access: yesBMC Public Health
Introduction Workplace violence (WPV) is one of the major challenges confronting healthcare workers in the developed and developing nations. Standard protocols for its prevention and management are essential for workplace safety in healthcare ...
Oluwaseyi Isaiah Olabisi   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy