Results 121 to 130 of about 6,634,184 (388)

Pre-operative optimisation employing dopexamine or adrenaline for patients undergoing major elective surgery: a cost-effectiveness analysis [PDF]

, 2002
<b>Objective</b>: To compare the cost and cost-effectiveness of a policy of pre-operative optimisation of oxygen delivery (using either adrenaline or dopexamine) to reduce the risk associated with major elective surgery, in high-risk patients.
Claxton, K., Fenwick, E., Sculpher, M.J., Wilson, J.   +3 more
core   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Uso da aspiração manual a vácuo na redução do custo e duração de internamentos por aborto incompleto em Fortaleza, CE, Brasil

Revista de Saúde Pública
INTRODUÇÃO: O uso de aspiração a vácuo (AV) no tratamento do aborto incompleto é prática bastante difundida em países desenvolvidos. Vários estudos nesses países indicam que o uso da técnica de aspiração manual a vácuo (AMV) pode conservar recursos do ...
Walter Fonseca, Chizuru Misago, Lucília Fernandes, Luciano Correia, Dirlene Silveira   +4 more
doaj  

Outcomes and costs of blunt trauma in England and Wales [PDF]

, 2008
Background Trauma represents an important public health concern in the United Kingdom, yet the acute costs of blunt trauma injury have not been documented and analysed in detail. Knowledge of the overall costs of trauma care, and the drivers of these
Christensen, MC, Lecky, FE, Morris, S, Munro, V, Ridley, S   +4 more
core   +2 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Impact of clinical pathways on hospital costs and early outcome after major vascular surgery [PDF]

, 1995
Keith D. Calligaro, Matthew J. Dougherty, Carol A. Raviola, David J. Musser, Dominic A. DeLaurentis   +4 more
openalex   +1 more source

Effect of Postoperative Pain Management after Robot-Assisted Radical Prostatectomy: A Study on Reducing Hospital Length of Stay and Medical Costs Using Japanese Nationwide Database

, 2022
Miki Mizuta, Kunio Tarasawa, Kiyohide Fushimi, Kenji Fujimori   +3 more
openalex   +2 more sources

Costs analysis of Staged Versus Simultaneous Bilateral Total Knee and Hip Arthroplasty: a university affiliated hospital survey of 1579 Chinese patients [PDF]

, 2020
Ji-Fei Hou, Chuan Hu, Yun Zhang, Yanzheng Liu, Chi Zhang, Jing Li   +5 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source