Results 121 to 130 of about 942,874 (288)

"Palliative Syringe Driver"? A Mixed-Methods Study in Different Hospital Departments on Continuous Infusions of Sedatives and/or Opioids in End-of-Life Care. [PDF]

J Patient Saf, 2022
Meesters S, Grüne B, Bausewein C, Schildmann E.   +3 more
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Chronic Kidney Disease Patients Visiting Various Hospital Departments: An Analysis in a Hospital in Central Tokyo, Japan. [PDF]

J Pers Med, 2022
Fukui A, Takeshita K, Nakashima A, Maruyama Y, Yokoo T.   +4 more
europepmc   +1 more source

Home is Where the Hurt is: An Econometric Analysis of Injuries Caused By Spousal Assault [PDF]

Using data on injuries presenting at the emergency departments of participating hospitals in the Australian state of Queensland we examine the nature of injuries resulting from spousal assault and compare them to injuries from nonspousal assault and ...
Borooah, Vani, Mangan, John
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Analysis of antibiotic use in an intensive care unit of a county hospital

Applied Medical Informatics, 2019
Introduction: National data on the consumption of antibiotics in hospital are relatively just a few, therefore a comparative analysis of this consumption is limited.
Viviana HODOŞAN, Petru COTRĂU, Cristian M DAINA, Carmen PANTIȘ, Adriana VLADU, Marcel NEGRAU, Lucia G DAINA   +6 more
doaj  

Availability, timeliness, documentation and quality of consultations among hospital departments: a prospective, comparative study. [PDF]

Isr J Health Policy Res, 2021
Jarjou'i A, Mendlovic J, Dadon Z, Sneineh MA, Tabi M, Kalak G, Jarallah YR, Yinnon AM, Munter G.   +8 more
europepmc   +1 more source

Injection of clarity needed? [PDF]

, 2003
The legal status of children who stay in hospital for three months or longer gives rise to considerable confusion among managers in social services and social work departments. And the number of young people affected is significant.
Carpenter, J., Connors, C., Phillips, R., Stalker, K.   +3 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

The Impact of Burnout Towards Organizational Citizenship Behavior (OCB) in Premier Surabaya Hospital [PDF]

, 2015
This research is conducted to know the impact of Burnout towards Organizational Citizenship Behavior (OCB), especially in Premier Surabaya Hospital. In addition, it also wants to compare the Burnout level between group of departments dealing directly ...
Kurniawan, F. (Fernaldi)
core