Results 11 to 20 of about 631,830 (259)

A Simulation Model for Logical and Operative Clash Detection [PDF]

, 2017
The introduction of the Building Information Modeling (BIM) approach has facilitated the management process of documents produced by different kinds of professionals involved in the design and/or renovation of a building, through identification and ...
Coraglia, UGO MARIA, Cursi, Stefano, D'Alessandro, Daniela, Fioravanti, Antonio, Simeone, Davide, Wurzer, Gabriel   +5 more
core   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

Pulling all the pedagogic pieces together to provide good electronic feedback: an example from science education [PDF]

, 2010
The aim of Nefreduca project was to develop digital science materials for chronically ill children and to assist them to cope more rationally with their illness.
Pinto, Roser, Saez, Marcel.la, Whitelock, Denise   +2 more
core  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Field hospitals to face COVID-19: Requirements and lessons learned in the design and construction of the Lagoa Barra Hospital - Brazil

Strategic Design Research Journal, 2020
The construction of field hospitals has been a strategy adopted worldwide to face the consequences of the pandemic impacts caused by COVID-19 on healthcare systems. Specific characteristics of this pandemic, such as different ways and speeds of the disease transmission, and the implications at the population health and the productive system, has made ...
C. K. Chinelli, K. S. de Matos Ferreira, A. P. Ribeiro, C. A. P. Soares   +3 more
openaire   +3 more sources

Building sustainability assessment: the case of hospital buildings [PDF]

, 2012
The hospital project contains different aspects from the most common projects of residential, office or service buildings. Designing a hospital environment is based in a number of criteria related to the satisfaction and well being of the working team ...
Bragança, L., Castro, Maria de Fátima Morais de Aguiar e, Mateus, Ricardo   +2 more
core  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Introducing a new technique for limb prepping in orthopedic surgeries: Designing, construction, and evaluation of limb-lifting assistive device [PDF]

, 2015
Lifting and holding patients' limbs while preparing the skin for orthopedic surgeries may be a lengthy process causing work-related musculoskeletal disorders (MSDs) for preoperative team members.
Mojeni, M.T., Najafi, S.A., Nomali, M.
core  

Noise Solver for Refurbishment Construction Site Design [PDF]

, 2018
The noise generated by the presence of a construction site within complex structure in operation (e.g. school, hospital) is a problem that too often is underestimated but that can generate problems of different nature, both concerning the health of the ...
Coraglia, Ugo Maria, Fioravanti, Antonio, Wurzer, Gabriel   +2 more
core   +2 more sources