Results 251 to 260 of about 645,045 (332)

Intravasation‐On‐µDevice (INVADE): Engineering Dynamic Vascular Interfaces to Study Cancer Cell Intravasation

open access: yesAdvanced Materials, EarlyView.
Cancer metastasis begins with intravasation, a complex process involving cancer‐endothelial interactions. INVADE (Intravasation‐on‐µDevice), a biomimetic microfluidic platform enables high‐throughput analysis of intravasation under controlled conditions.
Fengtao Jiang   +12 more
wiley   +1 more source

Engineering CRISPR System‐Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy

open access: yesAdvanced Materials, EarlyView.
This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang   +22 more
wiley   +1 more source

Artesunate Nanoplatform Targets the Serine–MAPK Axis in Cancer‐Associated Fibroblasts to Reverse Photothermal Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Materials, EarlyView.
The artesunate nanoplatform selectively targets ECM CAF, functioning as a GTPase inhibitor through disruption of intracellular serine homeostasis. This metabolic intervention effectively suppresses MAPK cascade activity, which consequently inhibits PTT‐induced CAF to ECM CAF differentiation.
Dongdong Zheng   +19 more
wiley   +1 more source

Organic AIE Nanoradiosensitizer Potentiates X‐Ray Triggered Continuous Reactive Oxygen Species Generation for Potent Cancer Radioimmunotherapy

open access: yesAdvanced Materials, EarlyView.
Herein, a glutathione‐responsive system (named THN) is prepared for X‐ray‐triggered sustained ROS generation for efficient antitumor immunotherapy. The double‐promoting ROS generation of THN induced massive immunogenic cancer cell death and polarized M2 macrophages into the M1 phenotype for enhanced antitumor immunotherapy.
Qingyong Xu   +10 more
wiley   +1 more source

Operating room (OR) requirements. [PDF]

open access: yesEur J Trauma Emerg Surg
Pfeifer R   +2 more
europepmc   +1 more source

Active Fabric Origami Enabled by Digital Embroidery of Magnetic Yarns

open access: yesAdvanced Materials, EarlyView.
This study demonstrates a scalable textile manufacturing process that fabricates active origami fabrics (AFO) via digital embroidery of magnetic yarns. The programmable AFO exhibits reversible 2D and 3D transformations under magnetic fields, enabling functionalities such as altering surface roughness and linear actuation.
Haiqiong Li   +3 more
wiley   +1 more source

Research on the online service mechanism of internet hospital in infectious disease prevention and control. [PDF]

open access: yesExp Biol Med (Maywood)
Zhao X   +10 more
europepmc   +1 more source

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