Results 171 to 180 of about 41,228 (244)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

A standardized framework for dietary intake data: implementation and monitoring of the 24-hour dietary recalls in the PROVEN-DIA trial. [PDF]

open access: yesFront Nutr
Fogaça AL   +7 more
europepmc   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 22, 12 June 2026.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang   +13 more
wiley   +1 more source

Digital vs. Direct Anthropometry with MetiSmile<sup>®</sup> 3D Face Scanner: A Validation and Reliability Study on a Mannequin Model. [PDF]

open access: yesCraniomaxillofac Trauma Reconstr
De Crem A   +8 more
europepmc   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

open access: yesAdvanced Science, Volume 13, Issue 32, 9 June 2026.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu   +15 more
wiley   +1 more source

Impact of single freeze-thaw cycles on human serum proteins: Implications for mass spectrometry biomarker validation. [PDF]

open access: yesiScience
Sauer T   +11 more
europepmc   +1 more source

Liver Kinase B1 in CD11c+ Cells Inhibits Fibrosis in Chronic Pancreatitis via the Oncostatin M Signaling

open access: yesAdvanced Science, Volume 13, Issue 32, 9 June 2026.
This study demonstrates significantly reduced Lkb1 expression in CD11c+ cells in chronic pancreatitis (CP) patients and animal models. Lkb1 deletion enhances CD11c+CD206+ macrophage infiltration and reprograms pancreatic stellate cells (PSCs) via OSM signaling.
Wenqing Zhang   +10 more
wiley   +1 more source

Factors Influencing the Use of G-CSF in Drug-Induced Agranulocytosis. [PDF]

open access: yesHematol Rep
Andrès E   +3 more
europepmc   +1 more source

Histovariability and fossil diagenesis of Pissarrachampsa (Pseudosuchia, Notosuchia, Baurusuchidae) from the Upper Cretaceous of Southeast Brazil

open access: yesThe Anatomical Record, Volume 309, Issue 6, Page 1451-1463, June 2026.
Abstract Notosuchians were key components of western Gondwanan Cretaceous ecosystems in terrestrial predator niches and exhibited remarkable taxonomic and ecological diversity. Previous research has explored their physiology, metabolism, and histology, revealing varied growth patterns and life history strategies.
Tito Aureliano   +5 more
wiley   +1 more source

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