Results 181 to 190 of about 3,593,101 (298)

Modbury Hospital waiting room photo

Black and white photo of the Modbury Hospital waiting ...
Modbury Hospital
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Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

Advanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang, Shilong Wang, Meng Wang, Ruixian Yu, Jingwu Yue, Lin Shao, Hui Zhang, Mengwen Zhu, Luyang Tian, Shuting Cheng, Weimin Qin, Yang Tang, Yi Han, Wenjia Wang, Liwei An, Yan Meng, Shi Jiao, Zhaocai Zhou   +17 more
wiley   +1 more source

Association Between Acute-Phase Occupational Therapy and Quality of Life at Hospital Discharge and 90 Days After Discharge. [PDF]

J Clin Med
Sato S, Nakanishi N, Watanabe S, Tanaka K, Morita Y, Liu K, Yasumura D, Tomoya N, Kudo G, Kozu R, Ishii K, Nakamura K, Oshima T, Katsukawa H.   +13 more
europepmc   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

General practice follow-up after hospital discharge in older adults: retrospective record analysis in UK primary care. [PDF]

Br J Gen Pract
Klepacz N, Long A, Shariff Z, Spencer SE, Mistry H, Griffiths F, Dale J, Spencer RA.   +7 more
europepmc   +1 more source

Modbury Hospital Photo album

Collection of colour and black and white photos of staff, patients and grounds of Modbury ...
Modbury Hospital
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Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

Advanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi, Guangying Li, Qian Yang, Rusun Liu, Linghan Gu, Mingmei Wang, John L. Waddington, Fuhai Ji, Xuechu Zhen   +8 more
wiley   +1 more source

Development and validation of the Patient Involvement in Medication Communication at Hospital discharge Questionnaire (PIMCH-Q). [PDF]

J Patient Rep Outcomes
Östman V, Bertilsson E, Cam H, Franzon K, Kälvemark Sporrong S, Frödén E, Shaat S, Gillespie U.   +7 more
europepmc   +1 more source

Modbury Hospital Cashier photo

Large Colour photo of a man talking to the cashier in the Modbury Hospital ...
Modbury Hospital
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An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source