Results 231 to 240 of about 5,635,190 (387)

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

open access: yesAdvanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu   +11 more
wiley   +1 more source

Opioid Prescribing for the Treatment of Acute Pain in Children on Hospital Discharge

open access: yesAnesthesia and Analgesia, 2017
C. Monitto   +17 more
semanticscholar   +1 more source

Provision of medication supply at hospital discharge: A rapid scoping review of the "Meds-to-Beds" care model. [PDF]

open access: yesAm J Health Syst Pharm
Muir A   +12 more
europepmc   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

open access: yesAdvanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong   +5 more
wiley   +1 more source

Incidence and Factors Associated with Breastfeeding at Six Months in Very-Low-Birthweight Infants: A Single-Center Prospective Study

open access: yesSiriraj Medical Journal
Objective: Primary objective was to determine success rate of breastfeeding (BF) at 6-month-postnatal age (PNA). Secondary objective was to explore factors associated with unsuccessful BF at 6-month-PNA in very-low-birthweight (VLBW) infants ...
Nutchayavaree Limpivilas   +4 more
doaj  

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

open access: yesAdvanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang   +16 more
wiley   +1 more source

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

open access: yesAdvanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu   +14 more
wiley   +1 more source

Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants.

open access: yesCochrane Database of Systematic Reviews, 2015
A. Spittle   +4 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy