Results 81 to 90 of about 254,153 (279)

Balancing conservation with national development: a socio-economic case study of the alternatives to the Serengeti Road [PDF]

, 2015
Developing countries often have rich natural resources but poor infrastructure to capitalize on them, which leads to significant challenges in terms of balancing poverty alleviation with conservation.
Bigurube, Gerald, Borner, Markus, Hopcraft, J. Grant C., Lembeli, James Daudi, Nugent, Rachel A.   +4 more
core   +3 more sources

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

HOSPITAL ADMISSIONS OF ADOLESCENTS DUE TO PRIMARY CARE SENSITIVE CONDITIONS IN A HEALTH REGION

Cogitare Enfermagem, 2018
Objective: To analyze hospital admissions due to primary care sensitive conditions in the 2nd Health Region of the State of Paraná in the 2010-2014 period.
Jéssyca Slompo Freitas, Maria Marta Nolasco Chaves, Vivian Patricia Raksa, Liliana Muller Larocca   +3 more
doaj   +1 more source

Assessing the association between oral hygiene and preterm birth by quantitative light-induced fluorescence [PDF]

, 2014
The aim of this study was to investigate the purported link between oral hygiene and preterm birth by using image analysis tools to quantify dental plaque biofilm.
Adeyemi, Adejumoke A., Burnside, Girvan, Higham, Susan M., Hope, Christopher K., Quenby, Siobhan, Smith, Philip W., Wang, Qian, Whitworth, Melissa   +7 more
core   +4 more sources

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

Advanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong, Jingyi Lu, Haopeng Li, Jun Zhong, Xiaobei Luo, Yiyi Hu, Xianfei Wang, Pengfei Wang, Yanning Zhang, Zhenjiang Wang, Qiuhua Lai, Zhenyu Chen, Wenting Mi, Wang Tin San‐to, Weize Li, Shuping Tan, Qihong Cheng, Ruijia Li, Yida Nie, Side Liu, Bing Huang, Zelong Han   +21 more
wiley   +1 more source

Suicide attempts in Brazil, 1998–2014: an ecological study

BMC Public Health, 2016
Background Attempted suicide is the main predictor of suicide constituting a major public health issue worldwide. It is estimated that for every completed suicide, 10 to 20 suicide attempts occur.
Davi Félix Martins Junior, Ridalva Martins Felzemburgh, Acácia Batista Dias, André C. Caribé, S. Bezerra-Filho, Ângela Miranda-Scippa   +5 more
doaj   +1 more source

Leveraging machine learning on the role of hospitalizations in the dynamics of dengue spread in Brazil: an ecological study of health systems resilience

The Lancet Regional Health - Americas
The alarming rise in dengue cases and fatalities worldwide necessitates an in-depth analysis of essential public health functions (EPHFs) to fortify the resilience of health systems in the face of upcoming surges. This study focuses on the resilience of Brazil's health system in managing dengue from 2010 to 2024, leveraging machine learning techniques ...
Paula de Castro-Nunes, Paloma Palmieri, Patrícia Passos Simões, Paulo Victor Rodrigues de Carvalho, Alessandro Jatobá   +4 more
openaire   +2 more sources

Spatial variation of heart failure and air pollution in Warwickshire, UK : an investigation of small scale variation at the ward-level [PDF]

, 2014
Objectives To map using geospatial modelling techniques the morbidity and mortality caused by heart failure within Warwickshire to characterise and quantify any influence of air pollution on these risks. Design Cross-sectional. Setting Warwickshire,
Bennett, Oscar, Clarke, Aileen, Ji, Chen, Kandala, Ngianga-Bakwin, Linnane, John   +4 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source