Results 161 to 170 of about 5,034,117 (336)

A cost‐effectiveness analysis of breast cancer treatment in certified versus non‐certified hospitals in Germany

International Journal of Cancer, EarlyView.
What's New? This study is the first to quantify the cost‐effectiveness of breast cancer treatment in German Cancer Society‐certified hospitals using real‐world data from over 140,000 patients. Analysis on certification‐related costs and survival outcomes demonstrates that high‐quality multidisciplinary care at certified hospitals delivers substantial ...
Min‐Wai Lwin, Olaf Schoffer, Christoph Streissnig, Pauline Wimberger, Michael Gerken, Veronika Bierbaum, Christoph Bobeth, Martin Rößler, Patrik Dröge, Thomas Ruhnke, Christian Günster, Kees Kleihues‐van Tol, Theresa Link, Anton Scharl, Elisabeth C. Sturm‐Inwald, Karin Kast, Thomas Papathemelis, Olaf Ortmann, Monika Klinkhammer‐Schalke, Jochen Schmitt, Michael Schlander   +20 more
wiley   +1 more source

Prediction of dose reductions and impact of reduced starting doses of CDK4/6i on effectiveness in HR‐positive/HER2‐negative metastatic breast cancer: Real‐world data from the OPAL registry

International Journal of Cancer, EarlyView.
What's New? Balancing efficacy and tolerability is challenging in oncology, as standard dosing often prioritizes maximum tolerated doses over other patient needs. Here, the authors developed a predictive index to identify patients with increased probability of dose reduction in metastatic breast cancer and compared the real‐world effectiveness of ...
Patrick Marschner, Kai Ringwald, Marc Thill, Mark‐Oliver Zahn, Anja Welt, Arnd Nusch, Gabriele Kaltenecker, Yolanda Rodemer, Volker Hagen, Caroline Schock, Lisa Kruggel, Anja Kaiser‐Osterhues, Dunja Klein, Nina Haug, Elmar Stickeler, Nadia Harbeck, Achim Wöckel, Norbert Marschner, Thomas Decker, the OPAL Registry Group   +19 more
wiley   +1 more source

Prediction of the individual risk for the development of brain metastases in patients with non‐oncogene‐addicted non‐small cell lung cancer: Real‐world data from the German prospective CRISP registry (AIO‐TRK‐0315)

International Journal of Cancer, EarlyView.
What's New? Estimating the risk of developing brain metastases may enable earlier diagnosis and treatment, potentially reducing morbidity and mortality. Using the prospective CRISP lung cancer registry, the authors developed and validated a point‐based classifier for the risk of developing first brain metastases in patients with advanced or metastatic ...
Fabian Acker, Katharina Wenger, Martin Reck, Cornelius F. Waller, Petra Hoffknecht, Andre Bethge, Arnd Nusch, Marcel Reiser, Christiane Bernhardt, Michael Bendel, Carolin Lennartz, Annette Fleitz, Martina Jänicke, Paula Ludwig, Annika Groth, Frank Griesinger, Michael Thomas, Wilfried E. E. Eberhardt, Martin Sebastian, for the CRISP Registry Group   +19 more
wiley   +1 more source

Fetal size, gestational age, and cognitive performance at 5 years in term‐born children: Four national cohorts' study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Fetal size and gestational age are essential factors to consider when determining the timing of delivery between mothers and obstetricians in term pregnancies. Previous studies have shown that both fetal size and gestational age have associations with cognitive or academic outcomes.
Xuan Zhao, Robert Eves, Siobhan Quenby, Sakari Lemola, Dieter Wolke   +4 more
wiley   +1 more source

Cost‐Effectiveness and Efficiency of Day Surgery Versus Elective Operations in Patients With Thyroid Neoplasms: A Multicenter Retrospective Cohort Study in China

iNew Medicine, EarlyView.
ABSTRACT Day surgery for thyroid malignancies is gaining traction globally, yet comprehensive health economic evaluations in China remain limited. This study evaluates the cost‐effectiveness and safety of thyroid day surgery versus elective inpatient operations using a large‐scale multicenter dataset.
Ying Wang, Hui Sun
wiley   +1 more source

Interpretable machine learning enables early and accurate detection of drug‐induced liver injury: A multicenter study with real‐world clinical translation

Interdisciplinary Medicine, EarlyView.
This study develops an interpretable gradient‐boosting model that accurately identifies drug‐induced liver injury (DILI) using routine laboratory data. The model explains key clinical features through SHapley Additive exPlanations analysis and detects DILI earlier than expert evaluation, offering a transparent and practical tool for precision ...
Jingyi Ling, Shian Zhang, Jun Lin, Zhengju Xu, Runcheng Xu, Qian Lv, Kaixiang Zhang, Sheng Liu, Jie Guo, Cheng Hua, Yin Jia, Xiaoyu Xu, Kun Qian, Shanrong Liu   +13 more
wiley   +1 more source

Group Agency and Egalitarian Corporate Structure: The Epistemic, Incentive, and Control Dimensions

Journal of Applied Philosophy, EarlyView.
ABSTRACT What constitutes a good corporate agent? The article answers this question by critically applying List and Pettit's theory of group agency, which emphasizes three crucial dimensions of organizational design: epistemic quality, incentive compatibility, and control.
Chi Kwok, Chris Man‐Kong Li
wiley   +1 more source

Minimum Volume Discussion in the Treatment of Colon and Rectal Cancer: A Review of the Current Status and Relevance of Surgeon and Hospital Volume regarding Result Quality and the Impact on Health Economics

Visceral Medicine, 2017
K. Link, P. Coy, M. Roitman, C. Link, M. Kornmann, L. Staib   +5 more
semanticscholar   +1 more source

Interventions for pre‐school children in foster care: A systematic review of the foster carer and system level outcomes from randomised controlled trials

JCPP Advances, EarlyView.
Abstract Background Children in foster care are at increased risk of experiencing cognitive, emotional and behavioural difficulties. There is a window of opportunity for early intervention associated with developmental sensitivity in the early years. Foster carers and the systems supporting them play a central role in intervention and support for the ...
Camilla Biggs, Natalie Kirby, Megan Garside, Gloria Cheung, Fiona Turner, Nishant Jaiswal, Helen Minnis   +6 more
wiley   +1 more source

Economic Pressure in Hospitals [PDF]

Deutsches Ärzteblatt international, 2017
openaire   +2 more sources