Results 161 to 170 of about 761,959 (281)

Combined Immediate‐Release and Extended‐Release Formulation of Sodium Valproate Provides Stable Plasma Levels for Inhibition of Histone Deacetylation

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract A modified controlled‐release sodium valproate formulation (VAL001, test) was compared with an approved enteric‐coated tablet formulation (Absenor, reference). Pharmacokinetics and safety/tolerability were evaluated in healthy subjects to bridge with positive efficacy results from an early‐phase patient trial of valproate in combination with ...
Nikhil Ahuja   +8 more
wiley   +1 more source

PHP64 Reorganisation of Hospital Emergency Services: A Business Case for Quality Improvement [PDF]

open access: bronze, 2011
Klaus Eichler   +5 more
openalex   +1 more source

Dynamic prediction of death risk given a renewal hospitalization process [PDF]

open access: yesarXiv
Predicting the risk of death for chronic patients is highly valuable for informed medical decision-making. This paper proposes a general framework for dynamic prediction of the risk of death of a patient given her hospitalization history, which is generally available to physicians.
arxiv  

CYP2C19 Polymorphisms and Clinical Outcomes Following Percutaneous Coronary Intervention in the Million Veteran Program

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 loss‐of‐function (LOF) alleles decrease the antiplatelet effect of clopidogrel following percutaneous coronary intervention (PCI) in patients presenting with acute coronary syndrome (ACS). The impact of genotype in patients undergoing PCI for stable ischemic heart disease (SIHD) in real‐world populations is less clear.
Catherine Chanfreau‐Coffinier   +20 more
wiley   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong   +9 more
wiley   +1 more source

The Public Sphere as a Meaningful Arena for Volunteering Dynamics: The Case of a Rural Space in Northern Israel

open access: yesConflict Resolution Quarterly, EarlyView.
ABSTRACT This article examines the context of the rural public sphere as reflected in residents' consciousness of their volunteering potential. To this end, a qualitative study was conducted in two rural settlements belonging to the same regional municipality in northern Israel: one Jewish and the other Arab. The 32 interviewees who participated in the
Yasmin Aboud‐Halabi   +1 more
wiley   +1 more source

Health disparities in chronic liver disease

open access: yesHepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian   +3 more
wiley   +1 more source

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