Background Admissions of infants in England have increased substantially but there is little evidence whether this is across the first year or predominately in neonates; and for all or for specific causes.
Eleanor Jones +6 more
doaj +1 more source
Short runs of atrial arrhythmia and stroke risk: a European-wide online survey among stroke physicians and cardiologists [PDF]
Methods: An online survey of cardiologists and stroke physicians was carried out to assess current management of patients with short runs of atrial arrhythmia within Europe. Results: Respondents included 311 clinicians from 32 countries.
Abdul-Rahim, A.H. +5 more
core +1 more source
Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying +8 more
wiley +1 more source
Under-reporting of roadcasualties ? phase 1 [PDF]
Although this report was commissioned by the Department for Transport, the findings and recommendations are those of the authors and do not necessarily represent the views of the ...
Lyons, R, Thoreau, R, Ward, H
core
An examination of who is eligible and who is receiving bariatric surgery in England : secondary analysis of the Health Survey for England dataset [PDF]
Background: Over 2 million people in England were estimated to be eligible for bariatric surgery in 2006. In 2014, clinical guidelines were updated, widening potential eligibility, meanwhile, obesity prevalence rose.
Desogus, Daniel +3 more
core +1 more source
Machine learning‐assisted surface‐enhanced Raman spectroscopy analysis of exosomal sialic acid for ovarian cancer diagnosis, as well as independent monitoring of exosomal sialic acid expression levels across different treatment periods, reveals a potential correlation with treatment response.
Lili Cong +6 more
wiley +1 more source
Background Valuable information on the determinants of non-fatal stroke can be obtained from longitudinal observational cohort studies. Such studies often rely on self-reported stroke events, which are best validated with external medical evidence.
Britton Annie +8 more
doaj +1 more source
Systematic review of therapeutic leave in inpatient mental health services [PDF]
AimTo identify, critically evaluate, and synthesise the empirical evidence about therapeutic leave from mental health inpatient settings.Background“Leave” occurs when a mental health inpatient exits the hospital ward with the appropriate authorisation ...
Barlow, Emily-May, Dickens, Geoffrey L.
core +5 more sources
Genetic Diagnosis and Discovery Enabled by Large Language Models
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu +25 more
wiley +1 more source
Impact of the National Institute for Health and Care Excellence (NICE) guidance on medical technology uptake: analysis of the uptake of spinal cord stimulation in England 2008-2012. [PDF]
This is the final version of the article. Available from the publisher via the DOI in this record.BACKGROUND: The National Institute for Health and Care Excellence (NICE) Technology Appraisal Guidance on spinal cord stimulation (SCS) was published in ...
Brookes, M +4 more
core +1 more source

