Left atrial appendage occlusion in the UK: prospective registry and data linkage to Hospital Episode Statistics. [PDF]
Willits I +10 more
europepmc +1 more source
Abstract Objective This study aimed to identify risk factors and develop a predictive scoring system for autoimmune‐associated epilepsy in subjects with autoimmune encephalitis presenting with new onset refractory status epilepticus (NORSE). Methods This retrospective, multicenter, cohort study included subjects who presented with NORSE at the onset of
Simona Lattanzi +50 more
wiley +1 more source
Association between hyperglycaemia, diabetes complications and development of fibrotic conditions among people living with type 1 and type 2 diabetes in England: a retrospective cohort study using UK Clinical Resource Datalink Aurum and Hospital Episode Statistics. [PDF]
Massen GM +11 more
europepmc +1 more source
Mechanisms of SCN2A loss of function do not predict presence or phenotype of epilepsy
Abstract Objective SCN2A loss‐of‐function (LoF) variants are associated with epilepsy (onset age ≥ 3 months), intellectual disability (ID), and autism spectrum disorder (ASD). Despite numerous identified variants and the description of phenotypic subgroups, relationships between Nav1.2 channel dysfunction and clinical phenotypes remain unclear.
Marsha Tan +23 more
wiley +1 more source
Abstract Objective Conceptualizing functional/dissociative seizures (FDS) as resulting from dissociation, or conversion, we hypothesized that, compared to epileptic seizures (ES), FDS should carry more symbolic or communicative content and that this would allow observers to distinguish FDS from ES.
Nayrin Dissouky +8 more
wiley +1 more source
Abstract Objective Posttraumatic stress disorder (PTSD) is more prevalent in epilepsy than in the general population. However, it remains unclear whether this association is specific to epilepsy or a broader consequence of experiencing unpredictable acute episodes within chronic diseases.
Lisa‐Dounia Soncin +9 more
wiley +1 more source
Changes in hip and knee arthroplasty practice post-COVID-19 in the English NHS: a retrospective analysis of hospital episode statistics data. [PDF]
Wainwright TW, Immins T, Middleton RG.
europepmc +1 more source
Abstract Objective Status epilepticus (SE) is the most severe expression of seizures, encompassing both SE with prominent motor symptoms and nonconvulsive SE (NCSE). Ictal–interictal continuum (IIC), an electroencephalographic phenomenon, is characterized by periodic discharges (PD), spike‐and‐waves or sharp‐and‐waves (SW), or lateralized rhythmic ...
Pilar Bosque‐Varela +15 more
wiley +1 more source
Evaluation of comorbidity measures for predicting mortality and revision surgery after elective primary shoulder replacement surgery based on data from the National Joint Registry and Hospital Episode Statistics for England: population based cohort study. [PDF]
Valsamis EM +5 more
europepmc +1 more source
KCNJ4 variants disrupt inward‐rectifier potassium channel function and cause refractory epilepsy
Abstract Objective Epilepsy is a common neurological disorder with a strong genetic basis, most frequently arising from ion channel dysfunction. Although multiple inwardly rectifying potassium (Kir) channels have been implicated in epileptogenesis, the contribution of KCNJ4, which encodes the Kir2.3 channel, has not previously been established in human
Hu Pan +20 more
wiley +1 more source

