Results 241 to 250 of about 46,400 (306)

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

Advanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu, Chao Xu, Jun Jiang, Limin He, Yike Zhou, Zhengxuan Li, Yu Li, Keying Zhang, Fa Yang, Tong Lu, Hongtao Song, Hai Zhu, Zhihao Hu, Xiaolong Zhao, Kai Gan, Hongji Li, Bo Yang, Rui Zhang, Weihong Wen, Donghui Han, Weijun Qin   +20 more
wiley   +1 more source

Meningitis outbreak in Gaza: the role of malnutrition, displacement and attacks on healthcare. [PDF]

BMJ Glob Health
Almadhoon H, Alqudwa Z, Tanous O, Mohareb AM, Kumar R, Wispelwey BP, Mills D.   +6 more
europepmc   +1 more source

Machine Learning‐Enhanced Ultrasensitive Immuno‐CRISPR Array Facilitates Early Diagnosis of Alzheimer's Disease by Detecting Multiple Plasma Biomarkers

Advanced Science, EarlyView.
This work presents a CRISPR‐based, ultrasensitive multiplex protein detection array capable of simultaneously analyzing six plasma biomarkers associated with Alzheimer's disease (AD). By integrating antibody‐mediated signal transduction, recombinase polymerase amplification, and spatially encoded CRISPR‐Cas12a, the system achieves detection sensitivity
Liding Zhang, Changwen Yang, Qian Yao, Xuewei Du, Shuai Ding, Yaoqiang Shi, Can Sheng, Ming Wang, Ying Han, Haiming Luo   +9 more
wiley   +1 more source

Second and third delays in emergency obstetric care: predictors in Northwest Cameroon. [PDF]

BMC Pregnancy Childbirth
Nkwain TJ, Navti LK, Atanga MBS.
europepmc   +1 more source

Availability of emergency drugs and essential resuscitation equipment and associated barriers in Addis Ababa Health Centers, Ethiopia: a mixed-methods study. [PDF]

Afr J Emerg Med
Mario LD, Feleke Y, Debebe F, Bawoke MM, Amha LG, Kefyalew M.   +5 more
europepmc   +1 more source

The framework and best practices of emergency medical teams: lessons learned from Israel's international field hospital response. [PDF]

Isr J Health Policy Res
Alpert EA, Weiser G, Kobliner-Friedman D, Schwaber MJ, Mayo A, Kedar R, Blumberg N, Merin O.   +7 more
europepmc   +1 more source

Assessment of infection prevention and control practices in healthcare facilities in the O.R. Tambo district municipality using the WHO infection prevention and control assessment framework. [PDF]

Front Public Health
Monwabisi D, Hosu MC, Mnqabashe YZJ, Nanjoh MK.   +3 more
europepmc   +1 more source

Overview and Preliminary Outcomes of a Children's Hospital Sponsored, Training Program Affiliated, School Based Dental Clinic. [PDF]

J Sch Health
Hammersmith KJ, Baer AC, Irwin MK, Townsend JA.   +3 more
europepmc   +1 more source