Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Predictive factors for recording the death of women of childbearing age in the Hospital Information System (SIH/SUS), Brazil, 2012-2020. [PDF]
Marques JA +5 more
europepmc +1 more source
Correlation between bone turnover and metabolic markers with age and gender: a cross-sectional study of hospital information system data. [PDF]
Shao J +5 more
europepmc +1 more source
Clinical information system post-adoption evaluation at the georges pompidou university hospital.
Jean-Marc Palm +4 more
openalex +1 more source
Users’ Perception of the Hospital Information System in a Maternity Hospital in Lampung, Indonesia
Al Asyary +3 more
openalex +2 more sources
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Associations between maternal body composition in the second trimester and premature rupture of membranes: a retrospective study using hospital information system data. [PDF]
Liao S +5 more
europepmc +1 more source
Important Points to Design Hospital Information System [PDF]
Hamid Moghaddasi
openalex +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Comparative risk of QTc prolongation induced by second-generation antipsychotics in the real world: retrospective cohort study based on a hospital information system. [PDF]
He L +6 more
europepmc +1 more source

