Results 81 to 90 of about 1,844,005 (241)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

The Role of GIS in Information System, Management and Decision Making in Hospitals and Ambulance Centers

International Journal of Body, Mind and Culture, 2017
The exclusive capabilities of Geographical Information System (GIS) cab be distinguished in combining diverse and very different information sources, in real-time storage and retrieval of descriptive and local information, in evaluation and analysis of ...
Sareh Aminzadeh, Mohammad Rabiee, Yousef Rezaei, Mostafa Bahmanabadi   +3 more
doaj  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Why does informatics work? Compensation strategies of the actors in the implementation of a medical prescription writing software - DOI: 10.3395/reciis.v2i1.159en

RECIIS, 2008
The present article describes the informatization process of a hospital service, taking as an example the implementation of a prescription writing software.
Gloria Zarama-Vasquez, Dominique Vinck
doaj  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

4145The impact of early warning information system on reducing in-hospital cardiac arrest [PDF]

, 2017
Shu‐Hung Kuo, Weixiao Huang, William Juan, Lin Kang, Wan‐Ting Hung, Cheng‐Hung Chiang, Shih-Kai Lin, Chin-Chang Cheng, Po Hsiang Lin, K. Y. Fong, David Hou, Shue Ren Wann, Guang-Yuan Mar, Y.S. Chen, C.P. Liu   +14 more
openalex   +1 more source

Effectiveness of Material Using CT Scan and MRI After Use of Picture Archiving and Commucating System and Radiology Information System at Radiological Installation of Bukit Tinggi National Hospital, West Sumatra [PDF]

, 2020
Adang Bachtiar
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Application of "Failure Modes and Effects Analysis" Method for improving of hospital information system

مدیریت اطلاعات سلامت, 2015
Introduction: Hospital environments are workplaces that have high risks with negative effects. About Health Information System (HIS), there are researches that show the negative effects of information technology applications in health care on patients ...
Mansoureh Naem Esfahani, Marzieh Javadi, Mina Azizzadeh   +2 more
doaj  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source