Results 151 to 160 of about 5,317,428 (385)

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Improving meaningful use and user experience of healthcare information systems towards better clinical outcomes

open access: yesFinnish Journal of eHealth and eWelfare, 2016
This paper outlines a practical approach for enabling user-centric healthcare information systems development in large scale. The approach is especially powerful at the current stage of clinical informatics adoption by the leading countries which have ...
Janne Pitkänen, Matti Pitkäranta
doaj  

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

International Profiles of Health Care Systems, 2012 [PDF]

open access: yes, 2012
This publication presents overviews of the health care systems of Australia, Canada, Denmark, England, France, Germany, Japan, Iceland, Italy, the Netherlands, New Zealand, Norway, Sweden, Switzerland, and the United States.

core  

eHealth: Towards a Healthcare Service-Oriented Boundary-Less Infrastructure [PDF]

open access: yesApplied Medical Informatics, 2010
The current paper presents several interoperability features applied to a local distributed information system, CardioNET, meant to improve quality of healthcare services, through the use of the latest medical and IT&C technologies.
Cristian LELUTIU   +5 more
doaj  

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

Considerations regarding the Performance Improvement of the Hospital Healthcare Services from Romania by the Implementation of an Integrated Management System [PDF]

open access: yes
The continuous quality improvement is an obligatory condition for the achievement and maintaining of the performance in healthcare services. Introducing the concepts of quality improvement in medical practice represents a distinctive component of the ...
Lelia Voinea, Rodica Pamfilie
core  

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

SISTEM RUMAH SAKIT TERPADU MENGGUNAKAN JSP (STUDI KASUS: TINDAKAN MEDIS RAWAT INAP) [PDF]

open access: yes, 2010
Final Project Report entitled "INTEGRATED HOSPITAL SYSTEM USING JSP (CASE STUDY: MEDICAL ACTION INPATIENT)". The purpose Writing objectives of this Final Project Report is to design information systems Inpatient Medical Action online at Regional General ...
Mubtada'i, Rosyid   +2 more
core  

Home - About - Disclaimer - Privacy