Results 161 to 170 of about 5,317,428 (385)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

SISTEM RUMAH SAKIT TERPADU MENGGUNAKAN JSP ( STUDY KASUS : GENERAL LEDGER TERINTEGRASI ) [PDF]

open access: yes, 2010
Final Project Report with the title "INTEGRATED HOSPITAL SYSTEM USING JSP (CASE STUDY: General Ledger INTEGRATED HOSPITAL)". The Purpose of the report writing the Final Projectt is to design a General Ledger system for the financial departmentt on ...
Mubtada'i, Nur   +2 more
core  

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Hospital specialists' private practice and its impact on the number of NHS patients treated and on the delay for elective surgery. [PDF]

open access: yes
This paper analyses UK NHS waiting times and waiting lists for elective surgery looking at the hospital specialists' behaviour and the conflict of interest these may face when allowed to practice privately.
Ana Xavier, Antonia Morga
core  

Information control and security policy in health care information systems [PDF]

open access: yes, 1994
The reliance on information systems forces the health care organizations to consider two security management issues: information control and security policy.
Clark, Lawrence, Lin, Binshan
core  

[Electronic patient files in hospital information systems]. [PDF]

open access: yesOphthalmologe, 2020
Mir Mohi Sefat A   +7 more
europepmc   +1 more source

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra   +17 more
wiley   +1 more source

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