Results 71 to 80 of about 947,668 (293)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

O Sistema de Informação Hospitalar e sua aplicação na saúde coletiva

open access: yesCadernos de Saúde Pública
O trabalho teve como objetivo levantar a produção científica das aplicações dos dados do Sistema de Informação Hospitalar do SUS (SIH/SUS) em análises de questões relevantes de Saúde Coletiva. Para a busca de artigos publicados em revistas científicas no
Sonia Azevedo Bittencourt   +2 more
doaj  

Selecting the Best End-User Device from User Perspective for Hospital Information Systems (HIS)

open access: yesمدیریت اطلاعات سلامت, 2015
Introduction: Choosing the right type of device is important to support users of Health Information Systems. In addition to cost, durability and simplicity, staffing levels and hospital workflows affect in the selected.
Mahboubeh Eslami   +2 more
doaj  

Current landscape of hospital information systems in gynecology and obstetrics in Germany: a survey of the commission Digital Medicine of the German Society for Gynecology and Obstetrics. [PDF]

open access: yesArch Gynecol Obstet, 2023
Pfob A   +10 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

User Satisfaction Regarding Hospital Information Systems: Structural Equation Modeling

open access: yesمدیریت اطلاعات سلامت, 2017
Introduction: User satisfaction is considered as the most important criterion of information system effectiveness. The aim of this study was to determine the factors affecting user satisfaction regarding hospital information systems. Methods: This was a
Leila Ranandeh-Kalankesh   +2 more
doaj  

Prospects of Hospital Information Systems and Patient Safety in Japan. [PDF]

open access: yesHealthc Inform Res, 2022
Nagoshi K, Watari T, Matsumura Y.
europepmc   +1 more source

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