Results 121 to 130 of about 421,252 (305)

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Hospital management of community-acquired pneumonia in Malta [PDF]

, 2012
Community-acquired pneumonia (CAP) remains a common diagnosis requiring hospital admission and a leading cause of death worldwide. No local guideline is currently available for the management of CAP.
Mamo, Jonathan, Micallef, Josef, Callus, Roberta, Montefort, Stephen   +3 more
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Pan-European early switch/early discharge opportunities exist for hospitalised patients with methicillin-resistant Staphylococcus aureus complicated skin and soft-tissue infections [PDF]

, 2014
The objective was to document pan-European real-world treatment patterns and healthcare resource use and estimate opportunities for early switch (ES) from intravenous (IV) to oral antibiotics and early discharge (ED) in hospitalised patients with ...
Solem, C.T., Haider, S., Macahilig, C., D. Simoneau, W. Lawson, C. Macahilig, Li, J.Z., Stephens, J.M., J.Z. Li, C. Eckmann, S. Haider, R. Chambers, J.M. Stephens, Simoneau, D., Eckmann, C., D. Nathwani, Lawson, W., C.T. Solem, Nathwani, D., Chambers, R., Li, J. Z.   +20 more
core   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Compound Heterozygote Friedreich Ataxia Patients With Covert Proximal FXN Gene Deletions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present Friedreich ataxia patients with frataxin gene deletions. Data and records were collected at the Children's Hospital of Philadelphia from patients enrolled in the FACOMS natural history study. Patients with proximal deletions initially diagnosed with only one GAA expanded allele had more severe disease than their homozygous expansion
Michael P. Lazaropoulos, Morgan C. Devore, Christina Lam, Courtney Park, Sanjay Bidichandani, David R. Lynch   +5 more
wiley   +1 more source

Does Hospital Competition Improve Efficiency? An Analysis of the Recent Market-Based Reforms to the English NHS [PDF]

This paper uses a difference-in-difference estimator to test whether the introduction of patient choice and hospital competition in the English NHS in January 2006 has prompted hospitals to become more efficient.
Zack Cooper, Alistair McGuire, Simon Jones, Steve Gibbons   +3 more
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Fluid overload is associated with increases in length of stay and hospital costs: pooled analysis of data from more than 600 US hospitals [PDF]

, 2013
Glenn Magee,1 Art Zbrozek21Premier Research Services, Charlotte, NC, USA; 2CSL Behring, King of Prussia, PA, USABackground: Fluid overload, including transfusion-associated circulatory overload (TACO), is a serious complication of fresh frozen plasma ...
Zbrozek A, Magee G
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Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

Impact of intravenous thrombolysis on length of hospital stay in cases of acute ischemic stroke [PDF]

, 2018
Narongrit Kasemsap,1,2 Nisa Vorasoot,1,2 Kannikar Kongbunkiat,1,2 Udomlack Peansukwech,1 Somsak Tiamkao,1,2 Kittisak Sawanyawisuth1,3,4 1Department of Medicine, Faculty of Medicine, 2North-Eastern Stroke Research Group, 3Research Center in Back, Neck ...
Peansukwech U, Tiamkao S, Kasemsap N, Kongbunkiat K, Sawanyawisuth K, Vorasoot N   +5 more
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