Results 91 to 100 of about 13,302,509 (331)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

An algorithm for the management of chronic obstructive pulmonary disease patients in units of internal medicine

Italian Journal of Medicine
Patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) are often hospitalized in internal medicine units (IMUs), and their management is challenging due to a multiplicity of factors affecting the outcome, such as correct ...
Ombretta Para, Carmen Stabile, Donato Cinquepalmi, Maria Sandra Magnoni, Francesco Nasso, Flavio Tangianu, Mauro Silingardi, Antonella Valerio, Dario Manfellotto, Francesco Dentali   +9 more
doaj   +1 more source

Strategies and Challenges for Managing Human Influenza in the Iranian hospitals: A Qualitative Study in Yazd province, Central part of Iran

Journal of Community Health Research, 2022
: Introduction: Influenza virus is one of the deadliest viruses that has threatened the human population over the years. Every year, organizations and hospitals must be prepared to deal with the disease and treat people with the flu and be able to manage
Sajjad Bahariniya, Milad Shafii, Farzan Madadizadeh, Mohammad Sharif Yazdi   +3 more
doaj  

Pre-hospital management of mass casualty civilian shootings: a systematic literature review

Critical Care, 2016
BackgroundMass casualty civilian shootings present an uncommon but recurring challenge to emergency services around the world and produce unique management demands.
Conor D. A. Turner, D. Lockey, M. Rehn
semanticscholar   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

SARS-CoV-2 Risk Management in Clinical Psychiatry: A Few Considerations on How to Deal With an Unrivaled Threat

Frontiers in Psychiatry, 2020
The pandemic spread of the corona virus SARS-CoV-2 has even-handedly shattered national and international health systems and economies almost in an instant.
Peter M. Kreuzer, Thomas C. Baghai, Rainer Rupprecht, Markus Wittmann, Dagmar Steffling, Michael Ziereis, Marc Zowe, Helmut Hausner, Berthold Langguth   +8 more
doaj   +1 more source

Use of Monitoring Indicators in Hospital Management of Antimicrobials [PDF]

, 2020
Ravena Melo Ribeiro da Silva, Ravena Melo Ribeiro da Silva, Simonize Cunha Barreto de Mendonça, Ingrid Novaes Leão, Quesia Santos, Alessandra Macedo Batista, Matheus Santos Melo, Milena da Motta Xavier, Lucindo José Quintans‐Júnior, Wellington da Silva, Iza Maria Fraga Lôbo   +10 more
openalex   +1 more source

4CPS-247 Initiatives to improve the management of patients with hereditary angioedema by hospital pharmacy [PDF]

, 2023
JB Montoro Ronsano, JM Martínez Sesmero, Ramón Lleonart Bellfill   +2 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Challenges Affecting the Implementation of Hospital Accreditation in Iran: An Interpretive Structural Modeling Approach

تحقیقات سلامت در جامعه, 2021
Introduction and purpose: Accreditation is a process in which a foreign institution systematically measures and evaluates the credibility of an organization in terms of process, outcome, and structural indicators.
Jamshid Bahmaei, Payam Shojaei, Mohammadsaeid Abbaszadeh, Mohammadtaghi Mohammadpour   +3 more
doaj