Results 41 to 50 of about 93,849 (210)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Patients' Perception of Waiting Time and Pharmacy Service of Hospital X Bali

Jurnal Manajemen dan Pelayanan Farmasi
Background: Many hospitals are having problems with waiting times. Meanwhile, the effect of waiting time on perceived pharmacy service quality is inconsistent.
Ni Putu Udayana Antari, Fitria Megawati, I Putu Tangkas Suwantara, I Gede Rizky Palguna, Ni Kadek Indah Amelia Widnyani, Ni Wayan Mita Sri Wahyuni   +5 more
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Evaluation of waiting time for outpatient services at Respira Hospital Yogyakarta using discrete system simulation

OPSI, 2023
The Ministry of Health of the Republic of Indonesia has established standard rules for the quality of outpatient service in hospitals. One indicator of the quality of outpatient services at a hospital is the patient's waiting time to be served either by ...
Yuli Dwi Astanti, Berty Dwi Rahmawati, Ahmad Taufiq Akbar, Alya Pangesti Rysnalendra   +3 more
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Evaluation of Pharmaceutical Services in Public Hospital Pharmacies of Federal District – Brazil [PDF]

Farmacia Hospitalaria, 2018
Objective: To evaluate pharmaceutical services in public hospital pharmacies of the Federal District Health Department – Brazil (Secretaria de Saúde do Distrito Federal, SES-DF).
Rodrigo Fonseca Lima, Janeth de Oliveira Silva Naves, Maria Inês de Toledo, Paulo Henrique Dourado Silva   +3 more
doaj   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree, Beatrice Suero, Sarah Walsh, Romain Marignier, John W. Lindsey, Ho Jin Kim, Dewei She, Daniel Cimbora, Dustin Cavida, Friedemann Paul   +9 more
wiley   +1 more source

Investigating ward nurses’ perceptions of hospital pharmacy service quality

Al-Sihah: The Public Health Science Journal
In recent years, organisations have increasingly focused their attention on internal service quality, which has a significant effect on customer satisfaction, which in turn impacts the performance of the organisation and ultimately profitability. However,
Patricia Bianca Chetty, Cornelius Bothma, Nombulelo Dilotsotlhe   +2 more
doaj   +1 more source

Medication Dispensing by Pharmacy Technicians Improves Efficiency and Patient Safety at a Geriatric Ward at a Danish Hospital: A Pilot Study

Pharmacy, 2023
Background: This study aims to evaluate medication dispensing by pharmacy technicians at a geriatric inpatient ward at a Danish hospital. Methods: Four pharmacy technicians were trained in delivering a dispensing service at a geriatric ward. At baseline,
Lene Juel Kjeldsen, Maja Schlünsen, Annette Meijers, Steffan Hansen, Camilla Christensen, Tanja Bender, Barbara Ratajczyk   +6 more
doaj   +1 more source