Results 41 to 50 of about 1,388,861 (350)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Kolaborasi Multidisiplin Pelaksanaan Discharge Planning

open access: yesAksiologiya: Jurnal Pengabdian Kepada Masyarakat, 2021
Discharge planning adalah suatu proses multidisplin yang melibatkan Profesioanal Pemberi Asuhan (PPA) dan Manajer Pelayanan Pasien (MPP) yang bertujuan untuk mengurangi lama tinggal atau perawatan di rumah sakit, mencegah terjadinya readmisi dan ...
Helmi Juwita   +3 more
doaj   +1 more source

Brave New Hospital (Apologies to Aldous Huxley) [PDF]

open access: yes, 2007
The migration to Mater Dei Hospital, our state of the art healthcare facility, has been completed. On the 19th of November 2007 the first acutely ill patients were admitted through the emergency department at Mater Dei Hospital!
Vassallo, Josanne
core  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Development of an Easy-to-Use Tool for the Assessment of Emergency Department Physical Design

open access: yesEmergency, 2014
Physical design of the emergency department (ED) has an important effect on its role and function. To date, no guidelines have been introduced to set the standards for the construction of EDs in Iran.
Alireza Majidi   +4 more
doaj  

Risk perception and choice of place of birth in women with high risk pregnancies: A qualitative study [PDF]

open access: yes, 2016
Objective: To examine the perception of risk among a group of women with high risk pregnancies who were either planning to give birth in hospital, or at home despite medical advice to the contrary.
Ayers, S., Holden, D., Lee, S.
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Strategi Bisnis RSU PKU Muhammadiyah Blora Melalui Pemetaan Faktor Internal dan Eksternal

open access: yesMagna Medika, 2016
The changing business environment demands hospital to adjust. the arrangement of strategic planning is required as of the hospital effort to answer the challenge off change.
Aisyah Lahdji
doaj   +1 more source

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