Results 41 to 50 of about 8,605,387 (387)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Discharge Planning

International Journal of Gerontology, 2012
Discharge planning is an interdisciplinary approach to continuity of care and a process that includes identification, assessment, goal setting, planning, implementation, coordination, and evaluation.
Chin-Jung Lin, Shih-Jung Cheng, Shou-Chuan Shih, Cheng-Hsin Chu, Jin-Jin Tjung   +4 more
doaj   +1 more source

Patient engagement in hospital health service planning and improvement: a scoping review

BMJ Open, 2018
Objectives Patient engagement (PE) improves patient, organisation and health system outcomes, but most research is based on primary care. The primary purpose of this study was to describe the characteristics of published empirical research that evaluated
Laurel Liang, Albina Cako, R. Urquhart, S. Straus, W. Wodchis, G. Baker, Anna R. Gagliardi   +6 more
semanticscholar   +1 more source

Determinants of hospital death in haematological cancers: findings from a qualitative study [PDF]

, 2017
© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. Objectives: Current UK health policy promotes enabling people to die in a place they choose, which for most is home.
Garry, Anne, Howard, Martin, Howell, Debra A., Johnson, Miriam, McCaughan, Dorothy, Patmore, Russell, Roman, Eve, Smith, Alexandra G.   +7 more
core   +2 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Predicting patient visits at the psychiatric polyclinic of a public hospital in Bali, Indonesia: A forecasting approach using single exponential smoothing

Journal of Healthcare Administration
Background: Hospital planning requires effective management of resources, facilities, and costs, and accurate patient visit forecasting is integral to this process.
Ni Made Ratih Comala Dewi Dewi, Putu Cintariasih, Ni Wayan Suryani, Luh Gde Nita Sri Wahyuningsih   +3 more
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Application of 3D printing and distributed manufacturing during the first-wave of COVID-19 pandemic. Our experience at a third-level university hospital

3D Printing in Medicine, 2021
Background 3D printing and distributed manufacturing represent a paradigm shift in the health system that is becoming critical during the COVID-19 pandemic. University hospitals are also taking on the role of manufacturers of custom-made solutions thanks
Rubén Perez-Mañanes, Sonia García-de San José, Manuel Desco-Menéndez, Ignacio Sánchez-Arcilla, Esmeralda González-Fernández, Javier Vaquero-Martín, Javier Pascau González-Garzón, Lydia Mediavilla-Santos, Diego Trapero-Moreno, José Antonio Calvo-Haro   +9 more
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Estimating the Impact of PM_2.5 on Hospital Burden from Respiratory and Cardiovascular Conditions in Southern Oregon: A Case-Crossover Analysis

Air
It is crucial to assess health impacts of PM2.5, especially from wildfire smoke, to ensure proper planning for healthcare services. Studies often focus on respiratory conditions; fewer estimate the additional burden of cardiovascular complications.
Anita Lee Mitchell, Kyle A. Chapman
doaj   +1 more source