Results 91 to 100 of about 8,394,614 (413)

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

The Danish health care system and epidemiological research: from health care contacts to database records

Clinical Epidemiology, 2019
Denmark has a large network of population-based medical databases, which routinely collect high-quality data as a by-product of health care provision.
M. Schmidt, S. Schmidt, K. Adelborg, J. Sundbøll, Kristina Laugesen, V. Ehrenstein, H. Sørensen   +6 more
semanticscholar   +1 more source

Despite Regulatory Changes, Hospitals Cautious in Helping Physicians Purchase Electronic Medical Records [PDF]

, 2008
Examines hospitals' strategies to aid physicians' adoption of electronic medical records (EMRs) following regulatory changes facilitating hospital-subsidized EMRs.
Genna R. Cohen, Joy M. Grossman
core  

Quality assessment of medical record as a tool for clinical risk management: a three year experience of a teaching hospital Policlinico Umberto I, Rome [PDF]

, 2017
Introduction: The medical record was defined by the Italian Ministry of Health in 1992 as "the information tool designed to record all relevant demographic and clinical information on a patient during a single hospitalization episode".
Bontempi, Claudio, Cacchio, Domenico, Catanzaro, Stefania, Chiarini, Massimiliano, Colamesta, Vittoria, DE GIUSTI, Maria, Ferro, Giuseppe, Guzzo, Anna Santa, Lombardi, ANNA MARIA, Marinelli, Enrico, Miani, Anna, Palazzo, Caterina, Salvati, Annunziata, Sposato, DOMENICA PATRIZIA, Tecca, Mario, Ursillo, Paolo   +15 more
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Cáncer mamario: Registro de Cáncer Clínica San Pedro Claver, 2003 Mammary cancer: Registry at Clinica San Pedro Claver

Revista Colombiana de Cirugía, 2005
Objetivo: Revisar los casos nuevos de cáncer mamario atendidos durante el año 2003 en la Clínica San Pedro Claver, Bogotá, Colombia. Material y métodos: La captación de las pacientes se hizo a través de la junta de seno, actividad a la cual asisten todas
Mario Arturo González Mariño
doaj  

A cross-sectional study of characteristics of bicyclist upper and lower extremity injuries in bicycle-vehicle crashes in Ohio, United States, 2013–2017

BMC Public Health, 2021
Background Extremity injury is one of the most common injury types for bicyclists. Extremity injury can lead to long-term disability and contribute to adverse health-related quality of life and prolonged absence from work.
Jodie Makara, Sijun Shen, Ann Nwosu, William Arnold, Gary Smith, Motao Zhu   +5 more
doaj   +1 more source

A survey of validity and utility of electronic patient records in a general practice [PDF]

, 2001
Objective: To develop methods of measuring the validity and utility of electronic patient records in general practice. Design: A survey of the main functional areas of a practice and use of independent criteria to measure the validity of the practice ...
Gerrett, D., Hassey, A., Wilson, A.
core   +2 more sources

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Data Resource Profile: ECHILD only-children and siblings (ECHILD-oCSib): a national cohort of linked health, education and social care data on mothers and children in England

International Journal of Population Data Science
Introduction Sibling dynamics play a crucial role in individual development, health and wellbeing. We established a national birth cohort using administrative health, education and social care data in England featuring clusters of mothers and their ...
Qi Feng, Georgina Ireland, Ruth Gilbert, Katie Harron   +3 more
doaj   +1 more source