Results 81 to 90 of about 107,401 (218)
Biomarkers of lung congestion and injury in acute heart failure
ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.Abstract
Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra +9 morewiley +1 more sourceAnalysis of the usefulness and benefits of ultrafiltration in cardiorenal syndrome: A systematic review
ESC Heart Failure, Volume 12, Issue 2, Page 1194-1202, April 2025.Abstract Aims
Cardiac decompensation in cardiorenal syndrome (CRS) results in systemic congestion usually treated with diuretics. When despite high doses of diuretics, response is poor, ultrafiltration (UF) appears to be a useful and safe technique.Borja Guerrero Cervera, Raquel López‐Vilella, Víctor Donoso Trenado, María Peris‐Fernández, Paula Carmona, Amparo Soldevila, Sergi Tormo, Ramón Devesa, María Jesús Montero Hernández, Luis Martínez Dolz, Julio Hernández Jaras, Pilar Sánchez‐Pérez, Luis Almenar‐Bonet +12 morewiley +1 more sourceCenobamate use in super‐refractory status epilepticus: A report of three cases
Epileptic Disorders, EarlyView.Abstract Objectives
Super‐refractory status epilepticus (SRSE) is a neurological emergency with high morbidity and mortality. Cenobamate, a novel antiseizure medication, may be helpful in managing SRSE, but evidence is limited. Methods
This retrospective case series reports the use of cenobamate as add‐on therapy in the management of three cases of ...Marina Romozzi, Juan Luis Alcala‐Zermeno, Antonio Funcis, Federico Tosto, Marta Piccioli, Luigi Francesco Iannone, Riccardo Maviglia, Masahito Katsuki, Yasuhiko Matsumori, Paolo Calabresi, Raffaele Iorio, Catello Vollono +11 morewiley +1 more sourcePediatric epilepsy surgery: Global survey of invasive explorations
Epilepsia, EarlyView.Abstract Objective
Invasive presurgical evaluation plays a key role in pediatric epilepsy surgery, particularly in magnetic resonance imaging (MRI)‐negative cases, by guiding resective, disconnective, or ablative procedures. This International League Against Epilepsy (ILAE) Pediatric Epilepsy Surgery Taskforce study provides an updated global overview ...Georgia Ramantani, Martha Feucht, Dorottya Cserpan, Javier Aparicio, Alexis Arzimanoglou, Fabrice Bartolomei, William Bingaman, Kees P. J. Braun, Richard J. Burman, Dezhi Cao, Roberto Caraballo, Mathilde Chipaux‐Raffo, Thomas Cloppenborg, J. Helen Cross, Arthur Cukiert, Cristine Mella Cukiert, Daniel J. Curry, Luca De Palma, Petia Dimova, Christin Eltze, Dario J. Englot, Johannes M. Nico Enslin, Aria Fallah, Stefano Francione, Deepak Gill, Tove Hallböök, A. Simon Harvey, Hans Holthausen, Sita Jayalakshmi, Yuwu Jiang, Lakshminarayanan Kannan, Matt Lallas, Sandeep Bhagwan Patil, María Ángeles Pérez‐Jiménez, Juan Carlos Pérez‐Poveda, Tom Pieper, Sabine Rona, Victoria San Antonio‐Arce, Jay Shetty, Mary Lou Smith, Piradee Suwanpakdee, Oana Tarta Arsene, Laura Tassi, Martin Tisdall, Manjari Tripathi, Ahsan Moosa Naduvil Valappil, Howard Weiner, Elaine Wirrell, Lixin Cai, Sarah Ferrand‐Sorbets, ILAE Pediatric Epilepsy Surgery Taskforce and Study Group, Carmen Barba, Marcelo Budke, James Butler, Poodipedi Sarat Chandra, Mary Connoly, Sameer Dal, Georg Dorfmüller, Noelle Enright, Siby Gopinath, Aris Hadjinicolaou, Masaki Iwasaki, Thilo Kalbhenn, Kalman A. Katlowitz, Kensuke Kawai, Takayuki Kikuchi, Katarzyna Kotulska‐Jóźwiak, Niklaus Krayenbühl, Martin Kudr, Noritsugu Kunihiro, Cassia Maniquis, Ailsa McLellan, Carolina Munoz Castro, Lino Nobili, Wim Otte, Manas Panigrahi, Veronica Pelliccia, Karl Rössler, Siraruj Sakoolnamarka, Didier Scavarda, Catalina Soto Órdenes, Nicola Specchio, Nigel Peter Symss, TS Dhanya, Olga Teo, Hartlieb Till, Dilşad Türkdoğan, Takehiro Uda, Vrajesh Udani, Shimrit Uliel‐Sibony, Naotaka Usui, Carlos Valera, Lejla Vendegh, Yi Wang, Jithangi Wanigasinghe, Jo Wilmshurst, Oscar Zorro Guio +96 morewiley +1 more sourceFirst‐Line Osimertinib in Patients with EGFR‐Mutant Advanced Non‐Small Cell Lung Cancer: Outcome and Safety in the Real World: FLOWER Study
The Oncologist, EarlyView., 2021 Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer.
Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation.
Patients with at least three metastatic sites, brain Martina Lorenzi, Alessandra Ferro, Fabiana Cecere, Daniela Scattolin, Alessandro Del Conte, Alessandro Follador, Sara Pilotto, Valentina Polo, Mariacarmela Santarpia, Rita Chiari, Alberto Pavan, Alessandro Dal Maso, Valentina Da Ros, Giada Targato, Sabrina Vari, Stefano Indraccolo, Fiorella Calabrese, Stefano Frega, Laura Bonanno, Pier Franco Conte, Valentina Guarneri, Giulia Pasello +21 morewiley +1 more sourceDiagnosis and management guidelines for infantile epileptic spasms syndrome around the world: A scoping review and comparative study of international approaches
Epilepsia, EarlyView.Abstract Objective
Infantile epileptic spasms syndrome (IESS) is an epileptic encephalopathy requiring rapid diagnosis and treatment to optimize neurodevelopmental outcomes. Although multiple national and regional guidelines exist, recommendations vary.Gozde Erdemir, Chethan K. Rao, Anne Francine Pino, Christina Briscoe, Debopam Samanta, Jo M. Wilmshurst, Sonal Bhatia, Jessica L. Carpenter, Christina Hoei‐Hansen, Puneet Jain, Tommy Stodberg, Robyn Whitney, Ryuki Matsuura, Karina Rosso Astorga, Keryma Acevedo Gallinato, Pratibha Singhi, Aristides Hadijinicolaou, Gia Melikishvili, Patricia Smeyers, Nicola Specchio, Stéphane Auvin, Pediatric Epilepsy Research Consortium Infantile Spasm Work Group and International Committee +21 morewiley +1 more sourceEffectiveness and tolerability of fenfluramine in pediatric and adult patients with developmental and epileptic encephalopathies: A multicenter, retrospective, real‐world clinical‐practice study
Epilepsia, EarlyView.Abstract Objective
Developmental and epileptic encephalopathies (DEEs) are characterized by drug‐resistant seizures and developmental slowing/regression. We examined the efficacy and tolerability of fenfluramine (FFA) in pediatric and adult patients with Lennox–Gastaut syndrome (LGS), Dravet syndrome (DS), and other DEEs.Vicente Villanueva, Elena González‐Alguacil, Patricia Smeyers, Sara Hernández, Victor Soto‐Insuga, Alejandro Fernández‐Cabrera, Laura Olivié, Teresa de Santos, Beatriz Parejo, Lucas Iacampo, Belén Ortuño, Javier Aparicio, Montserrat Fuentes, Juan Rodriguez‐Uranga, Paula Martínez‐Agredano, José Carlos Estévez, Angel Aledo‐Serrano, Rocio Martin‐Alvarez, David Conejo, Belen Baena, Blanca Mercedes‐Álvarez, Yolanda López, Alba Sierra‐Marcos, Rocio Trincado‐Lamuño, Mouna Ennazeh, Jesús González de la Aleja, Julia Renau, Maria Dolores Castro‐Vilanova, Fátima Romero‐Aguilera, José M. Serratosa +29 morewiley +1 more sourceProlonged fenfluramine use in open‐label studies of Dravet or Lennox–Gastaut syndromes: Long‐term safety, tolerability, patient global functioning, and considerations for interpreting effectiveness
Epilepsia, EarlyView.This graphical abstract provides an overview of the content from this open‐label extension study of fenfluramine use in patients with Dravet syndrome or Lennox‐Gastaut syndrome. Abstract Objective
Long‐term safety and global functioning are reported in patients with Dravet syndrome (DS) or Lennox–Gastaut syndrome (LGS) treated with fenfluramine in an ...Antonio Gil‐Nagel, Kelly G. Knupp, Boudewijn Gunning, Domenica Immacolata Battaglia, Elizabeth A. Thiele, Ingrid E. Scheffer, An‐Sofie Schoonjans, Rima Nabbout, Nathalie Villeneuve, Kerstin Alexandra Klotz, Nicola Specchio, Rocio Sanchez‐Carpintero, Marta Zolnowska, Anne‐Liv Schulz, Lily Perrin, Najla Dickson, Mélanie Langlois, Amélie Lothe, Joseph Sullivan +18 morewiley +1 more source64ª Semana do Hospital Universitário. Ano 2017
Anales de la Facultad de Medicina, 2017 Este año, la tradicional Semana Académica del Hospital de Clínicas de la Facultad de Medicina de la Universidad de la República, Uruguay, tuvo lugar del 4 al 8 de setiembre.Equipo Editorialdoaj