Results 161 to 170 of about 5,109,898 (358)
Role of the hospital in primary paediatric care [PDF]
J R Oakley, A Jay
openalex +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Neoliberalismo y reformas sanitarias en América Latina : una crítica a la concepción empresarial de los hospitales públicos [PDF]
Las reformas sanitarias orientadas al mercado implementadas a partir de la última década del siglo pasado pusieron en la mira a los hospitales públicos por tratarse de los centros asistenciales que consumen la mayor parte del presupuesto de salud.
Molina, Cecilia
core
Understanding Challenges to High-quality Pediatric Out-of-Hospital Cardiac Arrest Resuscitation Performance [PDF]
Amanda O’Halloran, Akira Nishisaki
openalex +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Diseño y propuesta de implementación de un plan de continuidad del negocio aplicable a los hospitales en la ciudad de Bogotá [PDF]
Trabajo de investigaciónTeniendo en cuenta la competencia en un mundo globalizado y así mismo expuesto día a día a diversas amenazas, se hace prioritario y menester la puesta en marcha de un Plan de Continuidad del Negocio, el cual permita que los ...
Velasco-Galeano, Heynner +1 more
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Re: Screening for retinopathy of prematurity and treatment outcome in a tertiary hospital in Hong Kong [PDF]
Karen KW Chan +3 more
openalex +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source

