Results 181 to 190 of about 5,109,898 (358)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Validación y aplicabilidad de encuestas SERVQUAL modificadas para medir la satisfacción de usuarios externos en servicios de salud

open access: yesRevista Médica Herediana, 2012
Objetivo: Validar y evaluar la aplicabilidad de encuestas para medir la satisfacción de los usuarios en consulta externa (CE) y emergencia (E) de un hospital público.
Emilio Cabello, Jesús L Chirinos
doaj  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Los médicos y los cirujanos mulatos y de otras castas en la Lima colonial

open access: yesFronteras de la Historia, 2014
En la Lima colonial, los mulatos libres y otras castas se hicieron imprescindibles como barberos y cirujanos a tal punto que esos oficios se volvieron casi exclusivos de ellos.
Paula Ermilia Rivasplata Varillas
doaj  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

The Matrimonial Maidens of downry for familiar and affective bows in three sevillian hospitals the old regime

open access: yesEstudios de Historia de España, 2019
The noble families protected the female surplus from their lineages, destining to this end testamentary wills, some of which were kept per centuries. Nevertheless not only they tried to protect to their own lineage, but to elite women which families had ...
Paula Ermila Rivasplata Varillas
doaj  

Hospitales en México

open access: yes, 2009
Para conceptuar el hospital actual en México debemos conocer a la perfección nuestro pasado, presente y futuro, la evolución de los hospitales desde la Conquista hasta el México posrevolucionario, la creación de hospitales para pobres y para ricos, que aún continúa; la beneficencia privada, la pública y el cambio de éstas con las Leyes de Reforma.
Mauro Loyo-Varela, Horacio Díaz-Chazaro
openaire   +1 more source

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