Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
763 Expanded and activated TILs kill tumor cells enabling IO compound assays
Paula Comune Pennacchi +10 more
doaj +1 more source
Beyond the knife: HDR plesiotherapy brings precision to atypical fibroxanthoma. [PDF]
Saiz C +13 more
europepmc +1 more source
Creación de un cuestionario de clima organizacional para hospitales de alta complejidad, Chile
Miguel A Bustamante-Ubilla +2 more
semanticscholar +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Transcranial static magnetic field stimulation of the primary motor cortex in essential tremor: a randomized pilot study. [PDF]
Urso D +6 more
europepmc +1 more source
Exploring the influence of austerity on the sustainability performance delivered within four Spanish hospital projects [PDF]
Martinez Fernadez, Laura, Thomson, Craig
core
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
[Impact of increased meeting frequency of the antimicrobial stewardship program team on indicators of the hospital use of antimicrobial agents based on consumption]. [PDF]
Zas-García MI +8 more
europepmc +1 more source

