Results 221 to 230 of about 4,574,187 (367)

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

open access: yesFEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu   +9 more
wiley   +1 more source

Characterization of ribosome heterogeneity during endothelial to hematopoietic transition

open access: yesFEBS Open Bio, EarlyView.
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian   +4 more
wiley   +1 more source

Feasibility, safety and efficacy of transauricular vagus nerve stimulation in a cohort of patients with disorders of consciousness

open access: yesBrain Stimulation, 2020
Enrique Noé   +7 more
doaj  

763 Expanded and activated TILs kill tumor cells enabling IO compound assays

open access: yesJournal for ImmunoTherapy of Cancer, 2020
Paula Comune Pennacchi   +10 more
doaj   +1 more source

[Efficient Management of Severe Asthma in the Clinic]. [PDF]

open access: yesOpen Respir Arch
Dávila I   +9 more
europepmc   +1 more source

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

open access: yesFEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno   +12 more
wiley   +1 more source

Comparison of percutaneous neuromodulation and therapeutic exercise in patients with chronic non-specific neck pain: a study protocol for a randomised controlled trial. [PDF]

open access: yesBMJ Open
Lara-Palomo IC   +6 more
europepmc   +1 more source

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